Smoking and lung cancer in Harbin, northeast China

J. Hu, C. Galeone, R. Lui, C. Pelucchi, C. La Vecchia, E. Negri

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

Background: We studied the relationship between smoking and lung cancer risk in Harbin, Heilongjiang province, northeast China, an area with a very high baseline risk of lung cancer in both sexes, using data from a case-control study of lung cancer conducted between 1987 and 1990. Patients and methods: Cases were 218 patients with incident, histologically confirmed lung cancer and controls were 436 patients admitted to the same hospital with non-neoplastic and non-lung diseases. Results: Compared with never-smokers, the multivariate odds ratio (OR) for current smokers was 3.47 [95% confidence interval (CI) 2.31-5.20], and for ex-smokers 1.53 (95% CI 0.81-2.87). Lung cancer risk increased by 20% (95% CI 14% to 28%) for an increment of 5 years in smoking duration, and by 29% (95% CI 15% to 45%) for an increment of five cigarettes per day. The OR for smokers reporting occupational exposure to selected known or likely lung carcinogens was 7.22, compared with non-smokers without occupational exposure. Conclusions: This study further confirms that cigarette smoking is a strong determinant of lung cancer also in this high-risk area of northeast China.

Original languageEnglish
Pages (from-to)1605-1608
Number of pages4
JournalAnnals of Oncology
Volume16
Issue number10
DOIs
Publication statusPublished - Oct 2005

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China
Lung Neoplasms
Smoking
Confidence Intervals
Occupational Exposure
Odds Ratio
Tobacco Products
Carcinogens
Case-Control Studies
Lung

Keywords

  • Case-control
  • China
  • Lung cancer
  • Smoking habit

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

Cite this

Hu, J., Galeone, C., Lui, R., Pelucchi, C., La Vecchia, C., & Negri, E. (2005). Smoking and lung cancer in Harbin, northeast China. Annals of Oncology, 16(10), 1605-1608. https://doi.org/10.1093/annonc/mdi312

Smoking and lung cancer in Harbin, northeast China. / Hu, J.; Galeone, C.; Lui, R.; Pelucchi, C.; La Vecchia, C.; Negri, E.

In: Annals of Oncology, Vol. 16, No. 10, 10.2005, p. 1605-1608.

Research output: Contribution to journalArticle

Hu, J, Galeone, C, Lui, R, Pelucchi, C, La Vecchia, C & Negri, E 2005, 'Smoking and lung cancer in Harbin, northeast China', Annals of Oncology, vol. 16, no. 10, pp. 1605-1608. https://doi.org/10.1093/annonc/mdi312
Hu J, Galeone C, Lui R, Pelucchi C, La Vecchia C, Negri E. Smoking and lung cancer in Harbin, northeast China. Annals of Oncology. 2005 Oct;16(10):1605-1608. https://doi.org/10.1093/annonc/mdi312
Hu, J. ; Galeone, C. ; Lui, R. ; Pelucchi, C. ; La Vecchia, C. ; Negri, E. / Smoking and lung cancer in Harbin, northeast China. In: Annals of Oncology. 2005 ; Vol. 16, No. 10. pp. 1605-1608.
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