TY - JOUR
T1 - Smoking and renal cell carcinoma
AU - La Vecchia, Carlo
AU - Negri, Eva
AU - D'Avanzo, Barbara
AU - Franceschi, Silvia
PY - 1990/9/1
Y1 - 1990/9/1
N2 - The relationship between smoking habits and the risk of renal cell carcinoma was investigated in a case-control study conducted in northern Italy on 131 cases of histologically confirmed cancers of the renal parenchyma (85 males, 46 females) and 394 controls in hospital for acute, nonneoplastic, nonurological disorders. Compared with never smokers, the relative risk (RR) was 1.7 (95% confidence interval = 1.0-3.1) among ex-smokers. A direct and significant dose-risk relationship was observed among current smokers, with RR of 1.1, 1.9, and 2.3 for moderate, intermediate, and heavy smokers. This trend in risk was statistically significant (χ2
1 = 5.04; P = 0.02). The risk was directly related with duration of smoking (RR = 1.7 for 20 years) and, among ex-smokers, with time elapsed since stopping (RR = 2.2 for
AB - The relationship between smoking habits and the risk of renal cell carcinoma was investigated in a case-control study conducted in northern Italy on 131 cases of histologically confirmed cancers of the renal parenchyma (85 males, 46 females) and 394 controls in hospital for acute, nonneoplastic, nonurological disorders. Compared with never smokers, the relative risk (RR) was 1.7 (95% confidence interval = 1.0-3.1) among ex-smokers. A direct and significant dose-risk relationship was observed among current smokers, with RR of 1.1, 1.9, and 2.3 for moderate, intermediate, and heavy smokers. This trend in risk was statistically significant (χ2
1 = 5.04; P = 0.02). The risk was directly related with duration of smoking (RR = 1.7 for 20 years) and, among ex-smokers, with time elapsed since stopping (RR = 2.2 for
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M3 - Article
C2 - 2386932
AN - SCOPUS:0025113616
VL - 50
SP - 5231
EP - 5233
JO - Journal of Cancer Research
JF - Journal of Cancer Research
SN - 0008-5472
IS - 17
ER -