Smoking habits and endometriosis risk among infertile women: Results from a case control study

Elisabetta Garavaglia, Elena Ricci, Raffaela Cioffi, Giuseppe Trojano, Alessandro Bulfoni, Fabio Parazzini, Paola Viganò

Research output: Contribution to journalArticle

Abstract

Some studies have suggested that tobacco smoking may affect the risk of endometriosis, but published data are controversial. We conducted a case control study on the association between smoking and endometriosis risk Cases of endometriosis included 90 women (median age 35, range 19-49) with incident, i.e. laparoscopically diagnosed within the year before interview, histologically confirmed endometriosis. Controls were 90 women (median age 35.5, range 17- 76) admitted for a wide spectrum of acute conditions unrelated to known potential risk factors for endometriosis. Compared with never smokers the OR of endometriosis was 2.36 (95% CI 1.04-5.35) in ever smokers. These findings were largely consistent in strata of age and education. Considering separately nulliparous and parous women the estimated OR of endometriosis in ever smokers were 1.51 (95%CI 0.26-11.36) and 2.52. In conclusion despite the limitations of this study the present analysis suggest that smoking may increase the risk of endometriosis in nulliparae women attending an infertility clinic: this finding may at least in part due to the effect of smoking on infertility.

Original languageEnglish
Pages (from-to)15-18
Number of pages4
JournalItalian Journal of Gynaecology and Obstetrics
Volume29
Issue number3
DOIs
Publication statusPublished - Sep 1 2017

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Endometriosis
Habits
Case-Control Studies
Smoking
Infertility
Interviews
Education

Keywords

  • Risk factor smoking endometriosis

ASJC Scopus subject areas

  • Obstetrics and Gynaecology

Cite this

Smoking habits and endometriosis risk among infertile women : Results from a case control study. / Garavaglia, Elisabetta; Ricci, Elena; Cioffi, Raffaela; Trojano, Giuseppe; Bulfoni, Alessandro; Parazzini, Fabio; Viganò, Paola.

In: Italian Journal of Gynaecology and Obstetrics, Vol. 29, No. 3, 01.09.2017, p. 15-18.

Research output: Contribution to journalArticle

Garavaglia, Elisabetta ; Ricci, Elena ; Cioffi, Raffaela ; Trojano, Giuseppe ; Bulfoni, Alessandro ; Parazzini, Fabio ; Viganò, Paola. / Smoking habits and endometriosis risk among infertile women : Results from a case control study. In: Italian Journal of Gynaecology and Obstetrics. 2017 ; Vol. 29, No. 3. pp. 15-18.
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