Smoking habits and non-Hodgkin's lymphoma: A case-control study in Northern Italy

A. Tavani, E. Negri, S. Franceschi, D. Serraino, C. La Vecchia

Research output: Contribution to journalArticle

33 Citations (Scopus)

Abstract

Background. A potential relationship between non-Hodgkin's lymphoma and tobacco smoking has been reported. This was further considered in a case- control study conducted in northern Italy in the provinces of Milan and Pordenone. Methods. A total of 429 cases of incident, histologically confirmed non-Hodgkin's lymphoma and 1,157 controls in hospital for acute, nonneoplastic, nonimmunological, non-tobacco-related diseases were interviewed during their hospital stay. Relative risk (RR) estimates and their 95% confidence intervals (CI), according to various measures of tobacco smoking, were derived from multiple logistic regression equations including terms for age, sex, study center, body mass index, and alcohol and coffee drinking. Results. Compared with that for never smokers, the multivariate RR was 1.0 (95% CI, 0.8 to 1.4) for both current smokers and ex-smokers. No trend in risk emerged with the number of cigarettes smoked per day (RR = 0.9, 95% CI, 0.7 to 1.3 for less than 20 cigarettes/day, and RR = 1.2, 95% CI, 0.8 to 1.8, for 20 or more cigarettes/day), or tar yield (RR = 1.2 for less than 17 mg, 1.0 for 17-20 mg, and 0.9 for more than 20 mg). Similarly, no trend in risk was observed with duration of smoking (RR = 1.0 for less than 30 years, 1.0 for 30-39 years, and 1.1 for 40 or more years) or age at starting smoking (RR = 1.1 for less than 20 years, 1.0 for 20-29 years, and 1.1 for 30 years or over) and, for ex-smokers, with time since quitting (RR = 1.1 for less than 10 years and 1.0 for 10 or more years of smoking cessation). Conclusions. The present study found no association between various measures of tobacco smoking and non-Hodgkin's lymphoma.

Original languageEnglish
Pages (from-to)447-452
Number of pages6
JournalPreventive Medicine
Volume23
Issue number4
DOIs
Publication statusPublished - 1994

Fingerprint

Non-Hodgkin's Lymphoma
Italy
Habits
Case-Control Studies
Smoking
Tobacco Products
Confidence Intervals
Tars
Coffee
Smoking Cessation
Alcohol Drinking
Length of Stay
Body Mass Index
Logistic Models

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Smoking habits and non-Hodgkin's lymphoma : A case-control study in Northern Italy. / Tavani, A.; Negri, E.; Franceschi, S.; Serraino, D.; La Vecchia, C.

In: Preventive Medicine, Vol. 23, No. 4, 1994, p. 447-452.

Research output: Contribution to journalArticle

Tavani, A. ; Negri, E. ; Franceschi, S. ; Serraino, D. ; La Vecchia, C. / Smoking habits and non-Hodgkin's lymphoma : A case-control study in Northern Italy. In: Preventive Medicine. 1994 ; Vol. 23, No. 4. pp. 447-452.
@article{86fbcde4bbe74b558cf06f3d76f2002d,
title = "Smoking habits and non-Hodgkin's lymphoma: A case-control study in Northern Italy",
abstract = "Background. A potential relationship between non-Hodgkin's lymphoma and tobacco smoking has been reported. This was further considered in a case- control study conducted in northern Italy in the provinces of Milan and Pordenone. Methods. A total of 429 cases of incident, histologically confirmed non-Hodgkin's lymphoma and 1,157 controls in hospital for acute, nonneoplastic, nonimmunological, non-tobacco-related diseases were interviewed during their hospital stay. Relative risk (RR) estimates and their 95{\%} confidence intervals (CI), according to various measures of tobacco smoking, were derived from multiple logistic regression equations including terms for age, sex, study center, body mass index, and alcohol and coffee drinking. Results. Compared with that for never smokers, the multivariate RR was 1.0 (95{\%} CI, 0.8 to 1.4) for both current smokers and ex-smokers. No trend in risk emerged with the number of cigarettes smoked per day (RR = 0.9, 95{\%} CI, 0.7 to 1.3 for less than 20 cigarettes/day, and RR = 1.2, 95{\%} CI, 0.8 to 1.8, for 20 or more cigarettes/day), or tar yield (RR = 1.2 for less than 17 mg, 1.0 for 17-20 mg, and 0.9 for more than 20 mg). Similarly, no trend in risk was observed with duration of smoking (RR = 1.0 for less than 30 years, 1.0 for 30-39 years, and 1.1 for 40 or more years) or age at starting smoking (RR = 1.1 for less than 20 years, 1.0 for 20-29 years, and 1.1 for 30 years or over) and, for ex-smokers, with time since quitting (RR = 1.1 for less than 10 years and 1.0 for 10 or more years of smoking cessation). Conclusions. The present study found no association between various measures of tobacco smoking and non-Hodgkin's lymphoma.",
author = "A. Tavani and E. Negri and S. Franceschi and D. Serraino and {La Vecchia}, C.",
year = "1994",
doi = "10.1006/pmed.1994.1061",
language = "English",
volume = "23",
pages = "447--452",
journal = "Preventive Medicine",
issn = "0091-7435",
publisher = "Academic Press Inc.",
number = "4",

}

TY - JOUR

T1 - Smoking habits and non-Hodgkin's lymphoma

T2 - A case-control study in Northern Italy

AU - Tavani, A.

AU - Negri, E.

AU - Franceschi, S.

AU - Serraino, D.

AU - La Vecchia, C.

PY - 1994

Y1 - 1994

N2 - Background. A potential relationship between non-Hodgkin's lymphoma and tobacco smoking has been reported. This was further considered in a case- control study conducted in northern Italy in the provinces of Milan and Pordenone. Methods. A total of 429 cases of incident, histologically confirmed non-Hodgkin's lymphoma and 1,157 controls in hospital for acute, nonneoplastic, nonimmunological, non-tobacco-related diseases were interviewed during their hospital stay. Relative risk (RR) estimates and their 95% confidence intervals (CI), according to various measures of tobacco smoking, were derived from multiple logistic regression equations including terms for age, sex, study center, body mass index, and alcohol and coffee drinking. Results. Compared with that for never smokers, the multivariate RR was 1.0 (95% CI, 0.8 to 1.4) for both current smokers and ex-smokers. No trend in risk emerged with the number of cigarettes smoked per day (RR = 0.9, 95% CI, 0.7 to 1.3 for less than 20 cigarettes/day, and RR = 1.2, 95% CI, 0.8 to 1.8, for 20 or more cigarettes/day), or tar yield (RR = 1.2 for less than 17 mg, 1.0 for 17-20 mg, and 0.9 for more than 20 mg). Similarly, no trend in risk was observed with duration of smoking (RR = 1.0 for less than 30 years, 1.0 for 30-39 years, and 1.1 for 40 or more years) or age at starting smoking (RR = 1.1 for less than 20 years, 1.0 for 20-29 years, and 1.1 for 30 years or over) and, for ex-smokers, with time since quitting (RR = 1.1 for less than 10 years and 1.0 for 10 or more years of smoking cessation). Conclusions. The present study found no association between various measures of tobacco smoking and non-Hodgkin's lymphoma.

AB - Background. A potential relationship between non-Hodgkin's lymphoma and tobacco smoking has been reported. This was further considered in a case- control study conducted in northern Italy in the provinces of Milan and Pordenone. Methods. A total of 429 cases of incident, histologically confirmed non-Hodgkin's lymphoma and 1,157 controls in hospital for acute, nonneoplastic, nonimmunological, non-tobacco-related diseases were interviewed during their hospital stay. Relative risk (RR) estimates and their 95% confidence intervals (CI), according to various measures of tobacco smoking, were derived from multiple logistic regression equations including terms for age, sex, study center, body mass index, and alcohol and coffee drinking. Results. Compared with that for never smokers, the multivariate RR was 1.0 (95% CI, 0.8 to 1.4) for both current smokers and ex-smokers. No trend in risk emerged with the number of cigarettes smoked per day (RR = 0.9, 95% CI, 0.7 to 1.3 for less than 20 cigarettes/day, and RR = 1.2, 95% CI, 0.8 to 1.8, for 20 or more cigarettes/day), or tar yield (RR = 1.2 for less than 17 mg, 1.0 for 17-20 mg, and 0.9 for more than 20 mg). Similarly, no trend in risk was observed with duration of smoking (RR = 1.0 for less than 30 years, 1.0 for 30-39 years, and 1.1 for 40 or more years) or age at starting smoking (RR = 1.1 for less than 20 years, 1.0 for 20-29 years, and 1.1 for 30 years or over) and, for ex-smokers, with time since quitting (RR = 1.1 for less than 10 years and 1.0 for 10 or more years of smoking cessation). Conclusions. The present study found no association between various measures of tobacco smoking and non-Hodgkin's lymphoma.

UR - http://www.scopus.com/inward/record.url?scp=0027997436&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0027997436&partnerID=8YFLogxK

U2 - 10.1006/pmed.1994.1061

DO - 10.1006/pmed.1994.1061

M3 - Article

C2 - 7971871

AN - SCOPUS:0027997436

VL - 23

SP - 447

EP - 452

JO - Preventive Medicine

JF - Preventive Medicine

SN - 0091-7435

IS - 4

ER -