Snazer: The simulations and networks analyzer

Tommaso Mazza, Gennaro Iaccarino, Corrado Priami

Research output: Contribution to journalArticle

Abstract

Background: Networks are widely recognized as key determinants of structure and function in systems that span the biological, physical, and social sciences. They are static pictures of the interactions among the components of complex systems. Often, much effort is required to identify networks as part of particular patterns as well as to visualize and interpret them.From a pure dynamical perspective, simulation represents a relevant way-out. Many simulator tools capitalized on the "noisy" behavior of some systems and used formal models to represent cellular activities as temporal trajectories. Statistical methods have been applied to a fairly large number of replicated trajectories in order to infer knowledge.A tool which both graphically manipulates reactive models and deals with sets of simulation time-course data by aggregation, interpretation and statistical analysis is missing and could add value to simulators.Results: We designed and implemented Snazer, the simulations and networks analyzer. Its goal is to aid the processes of visualizing and manipulating reactive models, as well as to share and interpret time-course data produced by stochastic simulators or by any other means.Conclusions: Snazer is a solid prototype that integrates biological network and simulation time-course data analysis techniques.

Original languageEnglish
Article number1
JournalBMC Systems Biology
Volume4
DOIs
Publication statusPublished - Jan 7 2010

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Electric network analyzers
Simulators
Simulator
Statistical methods
Trajectories
Simulation
Social sciences
Trajectory
Natural Science Disciplines
Biological Science Disciplines
Social Sciences
Large scale systems
Biological Networks
Agglomeration
Formal Model
Statistical method
Statistical Analysis
Complex Systems
Aggregation
Data analysis

ASJC Scopus subject areas

  • Molecular Biology
  • Structural Biology
  • Applied Mathematics
  • Modelling and Simulation
  • Computer Science Applications

Cite this

Snazer : The simulations and networks analyzer. / Mazza, Tommaso; Iaccarino, Gennaro; Priami, Corrado.

In: BMC Systems Biology, Vol. 4, 1, 07.01.2010.

Research output: Contribution to journalArticle

Mazza, Tommaso ; Iaccarino, Gennaro ; Priami, Corrado. / Snazer : The simulations and networks analyzer. In: BMC Systems Biology. 2010 ; Vol. 4.
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