Sneddon syndrome: Cerebral perfusion studies by Tc99M HM-PAO and SPECT

C. Canepari, S. Cappa, D. Perani, M. Riva, R. Sterzi, F. Fazio

Research output: Contribution to journalArticle


Sneddon syndrome is a non-inflammatory, non-atherosclerotic disease involving small and medium-sized arteries of the brain and of the skin. The arteriographic examination is often negative despite progressive impairment of the neurological status. In 3 patients with Sneddon syndrome cerebral perfusion was assessed with single photon emission computerized tomography (SPECT) and technetium99m-hexamethylpropylenamineoxime (Tc99 HM PAO). A correlation between clinical and SPECT finding was found, with significant focal reduction of regional cerebral blood flow (rCBF) in the two more severely affected patients.

Original languageEnglish
Pages (from-to)39-43
Number of pages5
JournalItalian Journal of Neurological Sciences
Issue number1
Publication statusPublished - Feb 1991


  • cerebral blood flow
  • Cerebrovascular disease
  • livedo reticularis
  • Sneddon syndrome

ASJC Scopus subject areas

  • Neuroscience(all)
  • Clinical Neurology

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