Sneddon's syndrome: clinical and immunohistochemical findings

Vincenza Fetoni, Emilio Berti, Emanuela Cecca, Francesco Carella, Renato Alberto Sinico, Floriano Girotti

Research output: Contribution to journalArticlepeer-review


Results of immunological studies on skin biopsies of 5 patients with Sneddon's syndrome are reported. Also studied were coagulation factors and autoantibodies believed to play a role in this syndrome. Hemostasis was normal except for a mild increase of fibrinogen in one subject; lupus anticoagulant (LAC) and anticardiolipin antibodies were negative in all. The skin biopsies ruled out systemic vasculitis and vasculitis in association with connective tissue diseases. Sneddon's syndrome is a peculiar clinico-pathological condition, probably with several etiologies, but is distinct from primary antiphospholipid syndrome.

Original languageEnglish
Pages (from-to)310-313
Number of pages4
JournalClinical Neurology and Neurosurgery
Issue number4
Publication statusPublished - 1994


  • Antiphospholipid antibodies
  • Livedo racemosa
  • Sneddon's syndrome

ASJC Scopus subject areas

  • Clinical Neurology
  • Surgery
  • Neurology


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