Sneddon's syndrome: clinical and immunohistochemical findings

Vincenza Fetoni, Emilio Berti, Emanuela Cecca, Francesco Carella, Renato Alberto Sinico, Floriano Girotti

Research output: Contribution to journalArticle

Abstract

Results of immunological studies on skin biopsies of 5 patients with Sneddon's syndrome are reported. Also studied were coagulation factors and autoantibodies believed to play a role in this syndrome. Hemostasis was normal except for a mild increase of fibrinogen in one subject; lupus anticoagulant (LAC) and anticardiolipin antibodies were negative in all. The skin biopsies ruled out systemic vasculitis and vasculitis in association with connective tissue diseases. Sneddon's syndrome is a peculiar clinico-pathological condition, probably with several etiologies, but is distinct from primary antiphospholipid syndrome.

Original languageEnglish
Pages (from-to)310-313
Number of pages4
JournalClinical Neurology and Neurosurgery
Volume96
Issue number4
DOIs
Publication statusPublished - 1994

Fingerprint

Sneddon Syndrome
Biopsy
Lupus Coagulation Inhibitor
Systemic Vasculitis
Anticardiolipin Antibodies
Skin
Connective Tissue Diseases
Blood Coagulation Factors
Antiphospholipid Syndrome
Vasculitis
Hemostasis
Autoantibodies
Fibrinogen

Keywords

  • Antiphospholipid antibodies
  • Livedo racemosa
  • Sneddon's syndrome

ASJC Scopus subject areas

  • Clinical Neurology
  • Surgery
  • Neurology

Cite this

Sneddon's syndrome : clinical and immunohistochemical findings. / Fetoni, Vincenza; Berti, Emilio; Cecca, Emanuela; Carella, Francesco; Sinico, Renato Alberto; Girotti, Floriano.

In: Clinical Neurology and Neurosurgery, Vol. 96, No. 4, 1994, p. 310-313.

Research output: Contribution to journalArticle

Fetoni, Vincenza ; Berti, Emilio ; Cecca, Emanuela ; Carella, Francesco ; Sinico, Renato Alberto ; Girotti, Floriano. / Sneddon's syndrome : clinical and immunohistochemical findings. In: Clinical Neurology and Neurosurgery. 1994 ; Vol. 96, No. 4. pp. 310-313.
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