Sodium balance and peripheral resistance in arterial hypertension

G. Bianchi, D. Cusi, C. Barlassina, C. Pati, M. G. Tripodi, E. Niutta, G. Vezzoli

Research output: Contribution to journalArticle

Abstract

In this brief review, some aspects of the relation between sodium balance and peripheral resistance in four types of arterial hypertension are discussed. Renal hypertension, hypertension caused by reduced kidney mass and sodium load, mineralocorticoid hypertension, and spontaneous or "genetic" hypertension in rats are considered. In all these forms of hypertension, the increase in peripheral resistance is preceded by changes in body sodium and fluids. However, the precise role of these changes in the development of the subsequent rise of peripheral resistance is not yet clear. Changes in ion transport across the cell membranes have been demonstrated even before the development of hypertension, especially the forms caused by mineralocorticoids or genetic factors. Even though we do not know the underlying mechanisms, it is very likely that these cell-membrane changes are involved in the rise of peripheral resistance and blood pressure.

Original languageEnglish
Pages (from-to)S457-S464
JournalJournal of Cardiovascular Pharmacology
Volume6
Publication statusPublished - 1984

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Vascular Resistance
Sodium
Hypertension
Mineralocorticoids
Cell Membrane
Renal Hypertension
Ion Transport
Body Fluids
Blood Pressure
Kidney

Keywords

  • Body fluids
  • Hypertension
  • Na balance
  • Peripheral resistance

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Pharmacology

Cite this

Bianchi, G., Cusi, D., Barlassina, C., Pati, C., Tripodi, M. G., Niutta, E., & Vezzoli, G. (1984). Sodium balance and peripheral resistance in arterial hypertension. Journal of Cardiovascular Pharmacology, 6, S457-S464.

Sodium balance and peripheral resistance in arterial hypertension. / Bianchi, G.; Cusi, D.; Barlassina, C.; Pati, C.; Tripodi, M. G.; Niutta, E.; Vezzoli, G.

In: Journal of Cardiovascular Pharmacology, Vol. 6, 1984, p. S457-S464.

Research output: Contribution to journalArticle

Bianchi, G, Cusi, D, Barlassina, C, Pati, C, Tripodi, MG, Niutta, E & Vezzoli, G 1984, 'Sodium balance and peripheral resistance in arterial hypertension', Journal of Cardiovascular Pharmacology, vol. 6, pp. S457-S464.
Bianchi G, Cusi D, Barlassina C, Pati C, Tripodi MG, Niutta E et al. Sodium balance and peripheral resistance in arterial hypertension. Journal of Cardiovascular Pharmacology. 1984;6:S457-S464.
Bianchi, G. ; Cusi, D. ; Barlassina, C. ; Pati, C. ; Tripodi, M. G. ; Niutta, E. ; Vezzoli, G. / Sodium balance and peripheral resistance in arterial hypertension. In: Journal of Cardiovascular Pharmacology. 1984 ; Vol. 6. pp. S457-S464.
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