Abstract
Primary bone sarcomas represent extremely rare entities. The use of now abolished labels, such as malignant fibrous histiocytoma and hemangiopericytoma, has significantly hampered the chance of identifying specific entities. It is now accepted that a broad variety of mesenchymal malignancies most often arising on the soft tissue may actually present as primary bone lesions. A more accurate morphologic partition is justified based on availability of distinct therapeutic options. An integrated diagnostic approach represents the only way to achieve a correct classification. In consideration of the significant complexity, primary bone sarcomas should ideally be handled in the context of expert centers.
| Original language | English |
|---|---|
| Pages (from-to) | 705-736 |
| Number of pages | 22 |
| Journal | Surgical Pathology Clinics |
| Volume | 10 |
| Issue number | 3 |
| DOIs | |
| Publication status | Accepted/In press - 2017 |
Fingerprint
Keywords
- Hemangiopericytoma
- Leiomyosarcoma of bone
- Malignant fibrous histiocytoma
- Primary sarcoma of bone
- Synovial sarcoma of bone
ASJC Scopus subject areas
- Surgery
- Pathology and Forensic Medicine
Cite this
Soft Tissue Tumors Rarely Presenting Primary in Bone; Diagnostic Pitfalls. / Sbaraglia, Marta; Righi, Alberto; Gambarotti, Marco; Vanel, Daniel; Picci, Piero; Dei Tos, Angelo P.
In: Surgical Pathology Clinics, Vol. 10, No. 3, 2017, p. 705-736.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Soft Tissue Tumors Rarely Presenting Primary in Bone; Diagnostic Pitfalls
AU - Sbaraglia, Marta
AU - Righi, Alberto
AU - Gambarotti, Marco
AU - Vanel, Daniel
AU - Picci, Piero
AU - Dei Tos, Angelo P.
PY - 2017
Y1 - 2017
N2 - Primary bone sarcomas represent extremely rare entities. The use of now abolished labels, such as malignant fibrous histiocytoma and hemangiopericytoma, has significantly hampered the chance of identifying specific entities. It is now accepted that a broad variety of mesenchymal malignancies most often arising on the soft tissue may actually present as primary bone lesions. A more accurate morphologic partition is justified based on availability of distinct therapeutic options. An integrated diagnostic approach represents the only way to achieve a correct classification. In consideration of the significant complexity, primary bone sarcomas should ideally be handled in the context of expert centers.
AB - Primary bone sarcomas represent extremely rare entities. The use of now abolished labels, such as malignant fibrous histiocytoma and hemangiopericytoma, has significantly hampered the chance of identifying specific entities. It is now accepted that a broad variety of mesenchymal malignancies most often arising on the soft tissue may actually present as primary bone lesions. A more accurate morphologic partition is justified based on availability of distinct therapeutic options. An integrated diagnostic approach represents the only way to achieve a correct classification. In consideration of the significant complexity, primary bone sarcomas should ideally be handled in the context of expert centers.
KW - Hemangiopericytoma
KW - Leiomyosarcoma of bone
KW - Malignant fibrous histiocytoma
KW - Primary sarcoma of bone
KW - Synovial sarcoma of bone
UR - http://www.scopus.com/inward/record.url?scp=85021329491&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85021329491&partnerID=8YFLogxK
U2 - 10.1016/j.path.2017.04.013
DO - 10.1016/j.path.2017.04.013
M3 - Article
AN - SCOPUS:85021329491
VL - 10
SP - 705
EP - 736
JO - Surgical Pathology Clinics
JF - Surgical Pathology Clinics
SN - 1875-9181
IS - 3
ER -