Soft Tissue Tumors Rarely Presenting Primary in Bone; Diagnostic Pitfalls

Marta Sbaraglia, Alberto Righi, Marco Gambarotti, Daniel Vanel, Piero Picci, Angelo P. Dei Tos

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Primary bone sarcomas represent extremely rare entities. The use of now abolished labels, such as malignant fibrous histiocytoma and hemangiopericytoma, has significantly hampered the chance of identifying specific entities. It is now accepted that a broad variety of mesenchymal malignancies most often arising on the soft tissue may actually present as primary bone lesions. A more accurate morphologic partition is justified based on availability of distinct therapeutic options. An integrated diagnostic approach represents the only way to achieve a correct classification. In consideration of the significant complexity, primary bone sarcomas should ideally be handled in the context of expert centers.

Original languageEnglish
Pages (from-to)705-736
Number of pages22
JournalSurgical Pathology Clinics
Volume10
Issue number3
DOIs
Publication statusAccepted/In press - 2017

Fingerprint

Bone and Bones
Sarcoma
Hemangiopericytoma
Malignant Fibrous Histiocytoma
Neoplasms
Therapeutics

Keywords

  • Hemangiopericytoma
  • Leiomyosarcoma of bone
  • Malignant fibrous histiocytoma
  • Primary sarcoma of bone
  • Synovial sarcoma of bone

ASJC Scopus subject areas

  • Surgery
  • Pathology and Forensic Medicine

Cite this

Soft Tissue Tumors Rarely Presenting Primary in Bone; Diagnostic Pitfalls. / Sbaraglia, Marta; Righi, Alberto; Gambarotti, Marco; Vanel, Daniel; Picci, Piero; Dei Tos, Angelo P.

In: Surgical Pathology Clinics, Vol. 10, No. 3, 2017, p. 705-736.

Research output: Contribution to journalArticle

Sbaraglia, Marta ; Righi, Alberto ; Gambarotti, Marco ; Vanel, Daniel ; Picci, Piero ; Dei Tos, Angelo P. / Soft Tissue Tumors Rarely Presenting Primary in Bone; Diagnostic Pitfalls. In: Surgical Pathology Clinics. 2017 ; Vol. 10, No. 3. pp. 705-736.
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