Abstract
The authors report 19 cases of solitary cerebral metastases from malignant malanoma. In 15 patients, the primary lesion was known at the time the metastasis was diagnosed; deltoid-scapular in 4 cases, thoracic in 5, inguinal in 4 and neck in 2. The primary location was unknown in 4 patients. Presenting symptoms were: epileptic seizures in 9 cases, headache in 8, strength deficit of the limbs in 2. In 3 patients (16%) neurological symptoms were the first clinical sign of the systemic tumor; in 16 cases (84%) there was a long interval between treatment of the primary and appearance of the cerebral metastasis (average 3.8 years; median 3.4 years). All patients were submitted to surgery and radiotherapy (whole-brain in 14 and radiosurgery in 5). In 10 cases the lesion was removed 'en bloc' (no internal touch technique). Average survival was 9 months (median 8 months) and was influenced by 'en bloc' resection and whole-brain irradiation. None of the patients operated by the 'no touch technique' presented a recurrence.
| Original language | English |
|---|---|
| Pages (from-to) | 12-14 |
| Number of pages | 3 |
| Journal | Clinical Neurology and Neurosurgery |
| Volume | 98 |
| Issue number | 1 |
| DOIs | |
| Publication status | Published - Feb 1996 |
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Keywords
- Brain
- Melanoma
- Single metastasis
- Treatment
ASJC Scopus subject areas
- Clinical Neurology
- Surgery
- Neurology
Cite this
Solitary cerebral metastasis from melanoma : Value of the 'en bloc' resection. / Salvati, Maurizio; Cervoni, Luigi; Caruso, Riccardo; Gagliardi, Franco Maria.
In: Clinical Neurology and Neurosurgery, Vol. 98, No. 1, 02.1996, p. 12-14.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Solitary cerebral metastasis from melanoma
T2 - Value of the 'en bloc' resection
AU - Salvati, Maurizio
AU - Cervoni, Luigi
AU - Caruso, Riccardo
AU - Gagliardi, Franco Maria
PY - 1996/2
Y1 - 1996/2
N2 - The authors report 19 cases of solitary cerebral metastases from malignant malanoma. In 15 patients, the primary lesion was known at the time the metastasis was diagnosed; deltoid-scapular in 4 cases, thoracic in 5, inguinal in 4 and neck in 2. The primary location was unknown in 4 patients. Presenting symptoms were: epileptic seizures in 9 cases, headache in 8, strength deficit of the limbs in 2. In 3 patients (16%) neurological symptoms were the first clinical sign of the systemic tumor; in 16 cases (84%) there was a long interval between treatment of the primary and appearance of the cerebral metastasis (average 3.8 years; median 3.4 years). All patients were submitted to surgery and radiotherapy (whole-brain in 14 and radiosurgery in 5). In 10 cases the lesion was removed 'en bloc' (no internal touch technique). Average survival was 9 months (median 8 months) and was influenced by 'en bloc' resection and whole-brain irradiation. None of the patients operated by the 'no touch technique' presented a recurrence.
AB - The authors report 19 cases of solitary cerebral metastases from malignant malanoma. In 15 patients, the primary lesion was known at the time the metastasis was diagnosed; deltoid-scapular in 4 cases, thoracic in 5, inguinal in 4 and neck in 2. The primary location was unknown in 4 patients. Presenting symptoms were: epileptic seizures in 9 cases, headache in 8, strength deficit of the limbs in 2. In 3 patients (16%) neurological symptoms were the first clinical sign of the systemic tumor; in 16 cases (84%) there was a long interval between treatment of the primary and appearance of the cerebral metastasis (average 3.8 years; median 3.4 years). All patients were submitted to surgery and radiotherapy (whole-brain in 14 and radiosurgery in 5). In 10 cases the lesion was removed 'en bloc' (no internal touch technique). Average survival was 9 months (median 8 months) and was influenced by 'en bloc' resection and whole-brain irradiation. None of the patients operated by the 'no touch technique' presented a recurrence.
KW - Brain
KW - Melanoma
KW - Single metastasis
KW - Treatment
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UR - http://www.scopus.com/inward/citedby.url?scp=0030028926&partnerID=8YFLogxK
U2 - 10.1016/0303-8467(95)00077-1
DO - 10.1016/0303-8467(95)00077-1
M3 - Article
VL - 98
SP - 12
EP - 14
JO - Clinical Neurology and Neurosurgery
JF - Clinical Neurology and Neurosurgery
SN - 0303-8467
IS - 1
ER -