Solitary cerebral metastasis from melanoma: Value of the 'en bloc' resection

Maurizio Salvati, Luigi Cervoni, Riccardo Caruso, Franco Maria Gagliardi

Research output: Contribution to journalArticle

Abstract

The authors report 19 cases of solitary cerebral metastases from malignant malanoma. In 15 patients, the primary lesion was known at the time the metastasis was diagnosed; deltoid-scapular in 4 cases, thoracic in 5, inguinal in 4 and neck in 2. The primary location was unknown in 4 patients. Presenting symptoms were: epileptic seizures in 9 cases, headache in 8, strength deficit of the limbs in 2. In 3 patients (16%) neurological symptoms were the first clinical sign of the systemic tumor; in 16 cases (84%) there was a long interval between treatment of the primary and appearance of the cerebral metastasis (average 3.8 years; median 3.4 years). All patients were submitted to surgery and radiotherapy (whole-brain in 14 and radiosurgery in 5). In 10 cases the lesion was removed 'en bloc' (no internal touch technique). Average survival was 9 months (median 8 months) and was influenced by 'en bloc' resection and whole-brain irradiation. None of the patients operated by the 'no touch technique' presented a recurrence.

Original languageEnglish
Pages (from-to)12-14
Number of pages3
JournalClinical Neurology and Neurosurgery
Volume98
Issue number1
DOIs
Publication statusPublished - Feb 1996

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Keywords

  • Brain
  • Melanoma
  • Single metastasis
  • Treatment

ASJC Scopus subject areas

  • Clinical Neurology
  • Surgery
  • Neurology

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