In 1972 Reed described a distinctive neoplasm of the skin, with the name of 'palisaded encapsulated neuroma'. This particular lesion is located specially on the face, and the histological examination reveals a dermal nodule well circumscribed, composed of Schwann cells and neuro-filaments. This tumour is diagnosed by histology and in differential diagnosis we have to consider the peripheral nerve tumours of the skin: neurofibromas, schwannomas and traumatic neuromas. We prefer the denomination of 'solitary circumscribed neuroma' (NSC), proposed by Fletcher, because it is more precise. The immunohistochemistry can confirm the diagnosis, and helps to differentiate NSC from the other nervous tumours of the skin. The pathogenesis of this tumour is unknown. The authors describe four cases of 'solitary circumscribed neuroma' of the skin, a neoplasm not frequently reported.
|Translated title of the contribution||Solitary circumscribed neuroma|
|Number of pages||3|
|Journal||Giornale Italiano di Dermatologia e Venereologia|
|Publication status||Published - 1995|
ASJC Scopus subject areas