Solitary fibrous tumor of the liver

Giovanni Vennarecci, Giuseppe Maria Ettorre, Luca Giovannelli, Franca del Nonno, Letizia Perracchio, Paolo Visca, Valerio Corazza, Antonello Vidiri, Giuseppe Visco, Eugenio Santoro

Research output: Contribution to journalArticle

Abstract

We report a new case of benign solitary fibrous tumor (SFT) of the liver. A 65-year-old man presented to our unit with upper right abdominal discomfort. On examination abdominal distension was present and palpation showed a large firm mass in the right hypochondrium and epigastrium. The patient's past medical history was not significant and laboratory tests were normal. Ultrasonography and computed tomography showed a large tumor, 20cm in diameter, in the right lobe of the liver. An extended right hepatectomy was performed. The tumor measured 30 × 28 × 14cm and weighed 4725g. Microscopic evaluation showed a benign SFT of the liver with tumor cells typically positive for vimentin and CD34. The postoperative course was uneventful, and the patient is alive 30 months after surgery. This is a rare neoplasm of mesenchymal origin that occasionally involves the liver in adult patients. Most SFTs are benign, but some may have malignant histological features and recur locally or metastasize. Because of their rarity, overall experience has not been significant and little has been published concerning this tumor, Including the present one, 28 cases have been reported in the English literature. Surgery is the mainstay of treatment. Little can be said about the benefits of adjuvant radiochemotherapy in these patients. As SFT of the liver is often a benign neoplasm, chemotherapy or radiotherapy should not be necessary, and should be reserved for when resection is incomplete and/or histological examination reveals features of malignancy. Surgeons must be aware of SFT of the liver, and this neoplasm should be included in the differential diagnosis of a single large hepatic mass.

Original languageEnglish
Pages (from-to)341-344
Number of pages4
JournalJournal of Hepato-Biliary-Pancreatic Surgery
Volume12
Issue number4
DOIs
Publication statusPublished - Aug 2005

Keywords

  • CD34
  • Liver disease
  • Liver tumor
  • Surgery
  • Vimentin

ASJC Scopus subject areas

  • Surgery

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  • Cite this

    Vennarecci, G., Ettorre, G. M., Giovannelli, L., del Nonno, F., Perracchio, L., Visca, P., Corazza, V., Vidiri, A., Visco, G., & Santoro, E. (2005). Solitary fibrous tumor of the liver. Journal of Hepato-Biliary-Pancreatic Surgery, 12(4), 341-344. https://doi.org/10.1007/s00534-005-0993-0