Solitary fibrous tumor of the pleura presenting with syncope episodes when coughing

Luigi Santambrogio, Mario Nosotti, Alessandro Palleschi, Lorenzo Rosso, Davide Tosi, Matilde De Simone, Michele M. Ciulla, Marco Maggioni, Ugo Cioffi

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Background: Solitary fibrous tumor of the pleura is a rarely encountered clinical entity which may have different clinical pictures. Although the majority of these neoplasms have a benign course, the malignant form has also been reported. Case presentation: We herein describe a case of 72 year-old man with head, facial, and thoracic traumas caused by neurally-mediated situational syncope when coughing. The diagnostic work-up including chest x-ray, CT and PET, revealed a large solitary mass of the left hemithorax. Radical surgical resection of the mass was performed through a left lateral thoracotomy and completed with a wedge resection of the lingula. Hystological examination of the surgical specimen showed an encapsulated mass measuring 12 × 11.5 × 6 cm consistent with a solitary fibrous tumor of the pleura. It's surgical removal definitively resolved the neurologic manifestations. The patient had no postoperative complications. At two years follow-up the patient is free from recurrence and without clinical manifestations. Conclusion: In ourcase its resection definitively resolved the episodes of situational syncope due, in our opinion, to the large thoracic mass compressing the phrenic nerve.

Original languageEnglish
Article number86
JournalWorld Journal of Surgical Oncology
Publication statusPublished - Aug 19 2008

ASJC Scopus subject areas

  • Cancer Research
  • Surgery


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