Abstract
PURPOSE OF REVIEW: Solitary fibrous tumor of the pleura (SFTP) is a rare neoplasm of the pleura. Although an increasing number of case series have been reported in recent years, so far clinical behavior is still unpredictable. The following article presents a detailed review of the recent larger series of SFTP with particular attention to the clinical presentation, pathologic characteristics and surgical features in order to define more precisely the long-term outcome after treatment of this rare entity. RECENT FINDINGS: Usually, after a complete surgical resection a very long survival could be expected in almost all cases. However, the preoperative detection and management of malignant SFTPs are still challenging issues. SUMMARY: SFTP remains an enigmatic tumor. Clinical and radiological assessment is often unsatisfactory to obtain a definitive diagnosis. Benign SFTPs are almost always cured with complete surgical resection, and in cases of recurrence the re-do resection of benign recurrences is usually curative. Long-term survivals are also possible for malignant SFTPs, although a higher recurrence rate and higher tumor-related mortality can be expected in these cases. Histologic characteristics distinguishing benign from malignant variants are crucial in estimating the risk of recurrence and planning adjuvant therapies.
| Original language | English |
|---|---|
| Pages (from-to) | 339-346 |
| Number of pages | 8 |
| Journal | Current Opinion in Pulmonary Medicine |
| Volume | 18 |
| Issue number | 4 |
| DOIs | |
| Publication status | Published - Jul 2012 |
Fingerprint
Keywords
- benign mesothelioma
- benign pleural tumor
- localized fibrous tumor of the pleura
- solitary fibrous tumor of the pleura
ASJC Scopus subject areas
- Pulmonary and Respiratory Medicine
Cite this
Solitary fibrous tumors of the pleura. / Cardillo, Giuseppe; Lococo, Filippo; Carleo, Francesco; Martelli, Massimo.
In: Current Opinion in Pulmonary Medicine, Vol. 18, No. 4, 07.2012, p. 339-346.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Solitary fibrous tumors of the pleura
AU - Cardillo, Giuseppe
AU - Lococo, Filippo
AU - Carleo, Francesco
AU - Martelli, Massimo
PY - 2012/7
Y1 - 2012/7
N2 - PURPOSE OF REVIEW: Solitary fibrous tumor of the pleura (SFTP) is a rare neoplasm of the pleura. Although an increasing number of case series have been reported in recent years, so far clinical behavior is still unpredictable. The following article presents a detailed review of the recent larger series of SFTP with particular attention to the clinical presentation, pathologic characteristics and surgical features in order to define more precisely the long-term outcome after treatment of this rare entity. RECENT FINDINGS: Usually, after a complete surgical resection a very long survival could be expected in almost all cases. However, the preoperative detection and management of malignant SFTPs are still challenging issues. SUMMARY: SFTP remains an enigmatic tumor. Clinical and radiological assessment is often unsatisfactory to obtain a definitive diagnosis. Benign SFTPs are almost always cured with complete surgical resection, and in cases of recurrence the re-do resection of benign recurrences is usually curative. Long-term survivals are also possible for malignant SFTPs, although a higher recurrence rate and higher tumor-related mortality can be expected in these cases. Histologic characteristics distinguishing benign from malignant variants are crucial in estimating the risk of recurrence and planning adjuvant therapies.
AB - PURPOSE OF REVIEW: Solitary fibrous tumor of the pleura (SFTP) is a rare neoplasm of the pleura. Although an increasing number of case series have been reported in recent years, so far clinical behavior is still unpredictable. The following article presents a detailed review of the recent larger series of SFTP with particular attention to the clinical presentation, pathologic characteristics and surgical features in order to define more precisely the long-term outcome after treatment of this rare entity. RECENT FINDINGS: Usually, after a complete surgical resection a very long survival could be expected in almost all cases. However, the preoperative detection and management of malignant SFTPs are still challenging issues. SUMMARY: SFTP remains an enigmatic tumor. Clinical and radiological assessment is often unsatisfactory to obtain a definitive diagnosis. Benign SFTPs are almost always cured with complete surgical resection, and in cases of recurrence the re-do resection of benign recurrences is usually curative. Long-term survivals are also possible for malignant SFTPs, although a higher recurrence rate and higher tumor-related mortality can be expected in these cases. Histologic characteristics distinguishing benign from malignant variants are crucial in estimating the risk of recurrence and planning adjuvant therapies.
KW - benign mesothelioma
KW - benign pleural tumor
KW - localized fibrous tumor of the pleura
KW - solitary fibrous tumor of the pleura
UR - http://www.scopus.com/inward/record.url?scp=84862230375&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84862230375&partnerID=8YFLogxK
U2 - 10.1097/MCP.0b013e328352f696
DO - 10.1097/MCP.0b013e328352f696
M3 - Article
C2 - 22450304
AN - SCOPUS:84862230375
VL - 18
SP - 339
EP - 346
JO - Current Opinion in Pulmonary Medicine
JF - Current Opinion in Pulmonary Medicine
SN - 1070-5287
IS - 4
ER -