Solitary fibrous tumors of the pleura

Giuseppe Cardillo, Filippo Lococo, Francesco Carleo, Massimo Martelli

Research output: Contribution to journalArticlepeer-review

Abstract

PURPOSE OF REVIEW: Solitary fibrous tumor of the pleura (SFTP) is a rare neoplasm of the pleura. Although an increasing number of case series have been reported in recent years, so far clinical behavior is still unpredictable. The following article presents a detailed review of the recent larger series of SFTP with particular attention to the clinical presentation, pathologic characteristics and surgical features in order to define more precisely the long-term outcome after treatment of this rare entity. RECENT FINDINGS: Usually, after a complete surgical resection a very long survival could be expected in almost all cases. However, the preoperative detection and management of malignant SFTPs are still challenging issues. SUMMARY: SFTP remains an enigmatic tumor. Clinical and radiological assessment is often unsatisfactory to obtain a definitive diagnosis. Benign SFTPs are almost always cured with complete surgical resection, and in cases of recurrence the re-do resection of benign recurrences is usually curative. Long-term survivals are also possible for malignant SFTPs, although a higher recurrence rate and higher tumor-related mortality can be expected in these cases. Histologic characteristics distinguishing benign from malignant variants are crucial in estimating the risk of recurrence and planning adjuvant therapies.

Original languageEnglish
Pages (from-to)339-346
Number of pages8
JournalCurrent Opinion in Pulmonary Medicine
Volume18
Issue number4
DOIs
Publication statusPublished - Jul 2012

Keywords

  • benign mesothelioma
  • benign pleural tumor
  • localized fibrous tumor of the pleura
  • solitary fibrous tumor of the pleura

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine

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