Metastasi umica metacrona dello sterno da adenocarcinoma del pancreas.

Translated title of the contribution: Solitary metachronous metastasis of the sternum from pancreatic adenocarcinoma

Cosimo Lequaglie, Aniello Della Morte, Elisa Feudale, Gabriella Giudice

Research output: Contribution to journalArticle

Abstract

Sternal metastases from adenocarcinoma of the pancreas are extremely rare, and even more so when solitary. Two years earlier, the patient reported on here, a 67-year-old man with a solitary osteolytic lesion of the sternal manubrium, had undergone a duodeno-cephalopancreatectomy for adenocarcinoma of the pancreas (G2, pY3, pN1) followed by adjuvant radio-chemotherapy. PET/CT scans, in response to the onset of burning pain in the sternal region, revealed a hypermetabolic area only at the level of the manubrium, while MRI showed a bulging manubrium due to the presence of extensive solid pathological tissue towards the right articulations of the ribs. Abnormal tumour markers were: CEA = 12, n.v. 0-4; Ca 15-3 = 512, n.v. 0-51, Ca 19-9 = 8777, n.v. 0-18. A partial sternectomy was performed with en-bloc resection of the hemiclavicles and the anterior tract of the 1st and 2nd ribs bilaterally with a mediastinic lymphadenectomy and repair with a sandwich prosthesis of prolene mesh and methacrylate, protecting the supra-aortic trunks and the anonymous vein with a polytetrafluoroethylene patch. The histological examination revealed secondary adenocarcinoma with 3 mediastinal metastatic lymph nodes. In view of the severe prognosis, a resection with palliative intent was also performed, which, when carried out in specialised centres, presents no contraindications in terms of cost-benefits.

Translated title of the contributionSolitary metachronous metastasis of the sternum from pancreatic adenocarcinoma
Original languageItalian
Pages (from-to)901-905
Number of pages5
JournalChirurgia Italiana
Volume59
Issue number6
Publication statusPublished - Nov 2007

ASJC Scopus subject areas

  • Surgery

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    Lequaglie, C., Della Morte, A., Feudale, E., & Giudice, G. (2007). Metastasi umica metacrona dello sterno da adenocarcinoma del pancreas. Chirurgia Italiana, 59(6), 901-905.