Solitary plasmacytoma of the spine: Relationship of IGM to tumour progression and recurrence

L. Cervoni, P. Celli, M. Salvati, R. Tarantino, A. Fortuna

Research output: Contribution to journalArticle

Abstract

The authors report a retrospective study of 15 patients with solitary vertebral plasmacytoma. 15 patients were considered in this study on the basis of the following characteristics: 1) histologically confirmed plasmacytoma following surgical removal; 2) existence of a single vertebral lesion, documented by skeletal and MRI scan; 3) no signs, at diagnosis of disseminated disease by blood laboratory test, urine analysis, sternal puncture, iliac bone marrow biopsy, a total-body CT scan. The clinical course of the patients has been analysed on the basis of the following factors: age, sex, length of clinical history before diagnosis, site, presence/absence of the M component. The M component is an electrophoretically homogeneous immunoglobin. The most significant factors for predicting development of multiple myeloma proved to be the presence/absence of the M component at diagnosis and, to a lesser degree, the age of the patient. In the light of other reports too, it would seem that the presence of the M component at diagnosis is a reflection of aggressive biological and clinical tumour behaviour.

Original languageEnglish
Pages (from-to)122-125
Number of pages4
JournalActa Neurochirurgica
Volume135
Issue number3-4
DOIs
Publication statusPublished - Sep 1995

Fingerprint

Myeloma Proteins
Plasmacytoma
Spine
Recurrence
Neoplasms
Sex Factors
Age Factors
Hematologic Tests
Multiple Myeloma
Punctures
Retrospective Studies
Bone Marrow
Magnetic Resonance Imaging
Urine
Biopsy

Keywords

  • multiple myeloma
  • Plasmacytoma of bone
  • spinal tumour

ASJC Scopus subject areas

  • Surgery
  • Clinical Neurology

Cite this

Solitary plasmacytoma of the spine : Relationship of IGM to tumour progression and recurrence. / Cervoni, L.; Celli, P.; Salvati, M.; Tarantino, R.; Fortuna, A.

In: Acta Neurochirurgica, Vol. 135, No. 3-4, 09.1995, p. 122-125.

Research output: Contribution to journalArticle

Cervoni, L, Celli, P, Salvati, M, Tarantino, R & Fortuna, A 1995, 'Solitary plasmacytoma of the spine: Relationship of IGM to tumour progression and recurrence', Acta Neurochirurgica, vol. 135, no. 3-4, pp. 122-125. https://doi.org/10.1007/BF02187754
Cervoni, L. ; Celli, P. ; Salvati, M. ; Tarantino, R. ; Fortuna, A. / Solitary plasmacytoma of the spine : Relationship of IGM to tumour progression and recurrence. In: Acta Neurochirurgica. 1995 ; Vol. 135, No. 3-4. pp. 122-125.
@article{0e8fca9107304a49842510dd57664c00,
title = "Solitary plasmacytoma of the spine: Relationship of IGM to tumour progression and recurrence",
abstract = "The authors report a retrospective study of 15 patients with solitary vertebral plasmacytoma. 15 patients were considered in this study on the basis of the following characteristics: 1) histologically confirmed plasmacytoma following surgical removal; 2) existence of a single vertebral lesion, documented by skeletal and MRI scan; 3) no signs, at diagnosis of disseminated disease by blood laboratory test, urine analysis, sternal puncture, iliac bone marrow biopsy, a total-body CT scan. The clinical course of the patients has been analysed on the basis of the following factors: age, sex, length of clinical history before diagnosis, site, presence/absence of the M component. The M component is an electrophoretically homogeneous immunoglobin. The most significant factors for predicting development of multiple myeloma proved to be the presence/absence of the M component at diagnosis and, to a lesser degree, the age of the patient. In the light of other reports too, it would seem that the presence of the M component at diagnosis is a reflection of aggressive biological and clinical tumour behaviour.",
keywords = "multiple myeloma, Plasmacytoma of bone, spinal tumour",
author = "L. Cervoni and P. Celli and M. Salvati and R. Tarantino and A. Fortuna",
year = "1995",
month = "9",
doi = "10.1007/BF02187754",
language = "English",
volume = "135",
pages = "122--125",
journal = "Acta Neurochirurgica",
issn = "0001-6268",
publisher = "Springer Wien",
number = "3-4",

}

TY - JOUR

T1 - Solitary plasmacytoma of the spine

T2 - Relationship of IGM to tumour progression and recurrence

AU - Cervoni, L.

AU - Celli, P.

AU - Salvati, M.

AU - Tarantino, R.

AU - Fortuna, A.

PY - 1995/9

Y1 - 1995/9

N2 - The authors report a retrospective study of 15 patients with solitary vertebral plasmacytoma. 15 patients were considered in this study on the basis of the following characteristics: 1) histologically confirmed plasmacytoma following surgical removal; 2) existence of a single vertebral lesion, documented by skeletal and MRI scan; 3) no signs, at diagnosis of disseminated disease by blood laboratory test, urine analysis, sternal puncture, iliac bone marrow biopsy, a total-body CT scan. The clinical course of the patients has been analysed on the basis of the following factors: age, sex, length of clinical history before diagnosis, site, presence/absence of the M component. The M component is an electrophoretically homogeneous immunoglobin. The most significant factors for predicting development of multiple myeloma proved to be the presence/absence of the M component at diagnosis and, to a lesser degree, the age of the patient. In the light of other reports too, it would seem that the presence of the M component at diagnosis is a reflection of aggressive biological and clinical tumour behaviour.

AB - The authors report a retrospective study of 15 patients with solitary vertebral plasmacytoma. 15 patients were considered in this study on the basis of the following characteristics: 1) histologically confirmed plasmacytoma following surgical removal; 2) existence of a single vertebral lesion, documented by skeletal and MRI scan; 3) no signs, at diagnosis of disseminated disease by blood laboratory test, urine analysis, sternal puncture, iliac bone marrow biopsy, a total-body CT scan. The clinical course of the patients has been analysed on the basis of the following factors: age, sex, length of clinical history before diagnosis, site, presence/absence of the M component. The M component is an electrophoretically homogeneous immunoglobin. The most significant factors for predicting development of multiple myeloma proved to be the presence/absence of the M component at diagnosis and, to a lesser degree, the age of the patient. In the light of other reports too, it would seem that the presence of the M component at diagnosis is a reflection of aggressive biological and clinical tumour behaviour.

KW - multiple myeloma

KW - Plasmacytoma of bone

KW - spinal tumour

UR - http://www.scopus.com/inward/record.url?scp=0029083561&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0029083561&partnerID=8YFLogxK

U2 - 10.1007/BF02187754

DO - 10.1007/BF02187754

M3 - Article

C2 - 8748800

AN - SCOPUS:0029083561

VL - 135

SP - 122

EP - 125

JO - Acta Neurochirurgica

JF - Acta Neurochirurgica

SN - 0001-6268

IS - 3-4

ER -