Soluble intercellular adhesion molecule-1 in sera from patients with chronic hepatitis C undergoing interferon treatment

A. M. Sonnante, R. Cozzolongo, R. Cuppone, G. De Michele, O. G. Manghisi, M. Quaranta

Research output: Contribution to journalArticlepeer-review

Abstract

To study the influence of interferon therapy on soluble intercellular adhesion molecule-1 we measured sICAM-1 levels in 22 patients with type C chronic hepatitis treated with interferon. We also studied 9 healthy subjects as control group. The results showed statistically significant higher levels of sICAM-1 in patients with liver disease than in the controls. The sICAM-1 baseline levels were similar in patients with chronic active hepatitis or cirrhosis but, during therapy, these levels decreased only in patients with chronic hepatitis. After IFN withdrawal sICAM-1 levels rebounded to initial values.

Original languageEnglish
Pages (from-to)567-569
Number of pages3
JournalArchives of Virology
Volume142
Issue number3
DOIs
Publication statusPublished - 1997

ASJC Scopus subject areas

  • Genetics
  • Applied Microbiology and Biotechnology

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