Soluble intercellular adhesion molecule-1 in sera from patients with chronic hepatitis C undergoing interferon treatment

A. M. Sonnante, R. Cozzolongo, R. Cuppone, G. De Michele, O. G. Manghisi, M. Quaranta

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

To study the influence of interferon therapy on soluble intercellular adhesion molecule-1 we measured sICAM-1 levels in 22 patients with type C chronic hepatitis treated with interferon. We also studied 9 healthy subjects as control group. The results showed statistically significant higher levels of sICAM-1 in patients with liver disease than in the controls. The sICAM-1 baseline levels were similar in patients with chronic active hepatitis or cirrhosis but, during therapy, these levels decreased only in patients with chronic hepatitis. After IFN withdrawal sICAM-1 levels rebounded to initial values.

Original languageEnglish
Pages (from-to)567-569
Number of pages3
JournalArchives of Virology
Volume142
Issue number3
DOIs
Publication statusPublished - 1997

Fingerprint

Chronic Hepatitis C
Intercellular Adhesion Molecule-1
Interferons
Chronic Hepatitis
Serum
Therapeutics
Liver Diseases
Healthy Volunteers
Fibrosis
Control Groups

ASJC Scopus subject areas

  • Genetics
  • Applied Microbiology and Biotechnology

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Soluble intercellular adhesion molecule-1 in sera from patients with chronic hepatitis C undergoing interferon treatment. / Sonnante, A. M.; Cozzolongo, R.; Cuppone, R.; De Michele, G.; Manghisi, O. G.; Quaranta, M.

In: Archives of Virology, Vol. 142, No. 3, 1997, p. 567-569.

Research output: Contribution to journalArticle

Sonnante, A. M. ; Cozzolongo, R. ; Cuppone, R. ; De Michele, G. ; Manghisi, O. G. ; Quaranta, M. / Soluble intercellular adhesion molecule-1 in sera from patients with chronic hepatitis C undergoing interferon treatment. In: Archives of Virology. 1997 ; Vol. 142, No. 3. pp. 567-569.
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