Soluble P-selectin as a marker of platelet hyperactivity in patients with chronic obstructive pulmonary disease

Patrizia Ferroni, Stefania Basil, Francesca Martini, Marco Vieri, Giancarlo Labbadia, Corrado Cordova, Cesare Alessandri, Pier Paolo Gazzaniga

Research output: Contribution to journalArticle

Abstract

A comparative analysis between soluble (s) P-selectin and von Willebrand Factor (vWF) was performed in 40 patients with chronic obstructive pulmonary disease (COPD) and 20 healthy subjects, with the aim of investigating whether the occurrence of elevated levels of sP-selectin may reflect activation of platelets, endothelial cells, or both. Plasma sP-selectin levels were significantly higher in patients compared to controls (P

Original languageEnglish
Pages (from-to)21-27
Number of pages7
JournalJournal of Investigative Medicine
Volume48
Issue number1
Publication statusPublished - Jan 2000

Keywords

  • Chronic obstructive pulmonary disease
  • Platelet activation
  • Soluble P-selectin

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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  • Cite this

    Ferroni, P., Basil, S., Martini, F., Vieri, M., Labbadia, G., Cordova, C., Alessandri, C., & Gazzaniga, P. P. (2000). Soluble P-selectin as a marker of platelet hyperactivity in patients with chronic obstructive pulmonary disease. Journal of Investigative Medicine, 48(1), 21-27.