Abstract
Increased expression of selectins has been found on endothelial cells of venules and capillaries in the tumor stroma of non-small cell lung cancer, suggesting their functional role in the process of chemotaxis for tumor cells. The present study was aimed at analyzing the role of both soluble (s)P-selectin and sE-selectin levels in association with clinicopathological variables in 116 patients with lung cancer, 38 patients with benign diseases and 59 healthy donors. The results obtained showed that sP-selectin and sE-selectin levels were higher in patients with lung cancer compared to normal donors (p
| Original language | English |
|---|---|
| Pages (from-to) | 56-62 |
| Number of pages | 7 |
| Journal | International Journal of Biological Markers |
| Volume | 17 |
| Issue number | 1 |
| Publication status | Published - 2002 |
Keywords
- E-selectin
- Lung cancer
- Metastasis
- P-selectin
- Soluble adhesion molecule
ASJC Scopus subject areas
- Immunology
- Biochemistry