Soluble selectin levels in patients with lung cancer

M. Roselli; T. C. Mineo; F. Martini; S. Mariotti; V. Ambrogi; A. Spila; R. D'Alessandro; S. Basili; F. Guadagni; Patrizia Ferroni

Soluble selectin levels in patients with lung cancer

M. Roselli, T. C. Mineo, F. Martini, S. Mariotti, V. Ambrogi, A. Spila, R. D'Alessandro, S. Basili, F. Guadagni, Patrizia Ferroni

Istituto San Raffaele Pisana

Research output: Contribution to journal › Article › peer-review

Abstract

Increased expression of selectins has been found on endothelial cells of venules and capillaries in the tumor stroma of non-small cell lung cancer, suggesting their functional role in the process of chemotaxis for tumor cells. The present study was aimed at analyzing the role of both soluble (s)P-selectin and sE-selectin levels in association with clinicopathological variables in 116 patients with lung cancer, 38 patients with benign diseases and 59 healthy donors. The results obtained showed that sP-selectin and sE-selectin levels were higher in patients with lung cancer compared to normal donors (p

Original language	English
Pages (from-to)	56-62
Number of pages	7
Journal	International Journal of Biological Markers
Volume	17
Issue number	1
Publication status	Published - 2002

Keywords

E-selectin
Lung cancer
Metastasis
P-selectin
Soluble adhesion molecule

ASJC Scopus subject areas

Immunology
Biochemistry

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title = "Soluble selectin levels in patients with lung cancer",

abstract = "Increased expression of selectins has been found on endothelial cells of venules and capillaries in the tumor stroma of non-small cell lung cancer, suggesting their functional role in the process of chemotaxis for tumor cells. The present study was aimed at analyzing the role of both soluble (s)P-selectin and sE-selectin levels in association with clinicopathological variables in 116 patients with lung cancer, 38 patients with benign diseases and 59 healthy donors. The results obtained showed that sP-selectin and sE-selectin levels were higher in patients with lung cancer compared to normal donors (p",

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T1 - Soluble selectin levels in patients with lung cancer

AU - Roselli, M.

AU - Mineo, T. C.

AU - Martini, F.

AU - Mariotti, S.

AU - Ambrogi, V.

AU - Spila, A.

AU - D'Alessandro, R.

AU - Basili, S.

AU - Guadagni, F.

AU - Ferroni, Patrizia

PY - 2002

Y1 - 2002

N2 - Increased expression of selectins has been found on endothelial cells of venules and capillaries in the tumor stroma of non-small cell lung cancer, suggesting their functional role in the process of chemotaxis for tumor cells. The present study was aimed at analyzing the role of both soluble (s)P-selectin and sE-selectin levels in association with clinicopathological variables in 116 patients with lung cancer, 38 patients with benign diseases and 59 healthy donors. The results obtained showed that sP-selectin and sE-selectin levels were higher in patients with lung cancer compared to normal donors (p

AB - Increased expression of selectins has been found on endothelial cells of venules and capillaries in the tumor stroma of non-small cell lung cancer, suggesting their functional role in the process of chemotaxis for tumor cells. The present study was aimed at analyzing the role of both soluble (s)P-selectin and sE-selectin levels in association with clinicopathological variables in 116 patients with lung cancer, 38 patients with benign diseases and 59 healthy donors. The results obtained showed that sP-selectin and sE-selectin levels were higher in patients with lung cancer compared to normal donors (p

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KW - Lung cancer

KW - Metastasis

KW - P-selectin

KW - Soluble adhesion molecule

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