Somatosensory evoked potentials in hemimegalencephaly and lissencephaly: anatomo-functional correlations

Matteo Di Capua, Federico Vigevano, Krystyna Wisniewski

Research output: Contribution to journalArticle


Four patients with hemimegalencephaly and four with lissencephaly were studied by median nerve somatosensory evoked potentials. The peripheral conduction velocity and the conduction time between the brachial plexus (Erb's point) and cervical cord were normal in both malformations. In hemimegalencephaly, the cortical components were absent on the malformed hemisphere but normal on the healthy side, whereas in lissencephaly an abnormal, prolonged N20 wave was recorded bilaterally. The difference presumably relates to the absence of normal cortical lamination in hemimegalencephaly and to the presence of a 'four-layered' cortex in lissencephaly.

Original languageEnglish
Pages (from-to)253-257
Number of pages5
JournalBrain and Development
Issue number4
Publication statusPublished - 1993


  • Cortical lamination
  • Hemimegalencephaly
  • Lissencephaly
  • Median nerve somatosensory evoked potential

ASJC Scopus subject areas

  • Clinical Neurology
  • Pediatrics, Perinatology, and Child Health
  • Neurology

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