Abstract
Withdrawal of a somatostatin infusion (SSIW) is followed by a rebound rise of GH in both animals and normal adult men, a phenomenon likely mediated by endogenous GHRH function. In the present study, we have evaluated the GH response to SSIW in a group of 28 prepubertal children (18 boys and 10 girls; aged 3.7-11.1 yr). Six children had GH deficiency [GHD; GH responses to pyridostigmine (PD)+GHRH and to clonidine 7 μg/L, respectively; mean integrated nighttime GH concentrations
| Original language | English |
|---|---|
| Pages (from-to) | 4426-4430 |
| Number of pages | 5 |
| Journal | Journal of Clinical Endocrinology and Metabolism |
| Volume | 84 |
| Issue number | 12 |
| Publication status | Published - 1999 |
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ASJC Scopus subject areas
- Biochemistry
- Endocrinology, Diabetes and Metabolism
Cite this
Cappa, M., Rigamonti, A. E., Bizzarri, C., Porzio, O., Civolani, P., Cella, S. G., Loche, S., & Müller, E. E. (1999). Somatostatin infusion withdrawal: Studies in normal children and in children with growth hormone deficiency. Journal of Clinical Endocrinology and Metabolism, 84(12), 4426-4430.