Translated title of the contribution: Some morpho-functional aspects of the frontal lobe

R. Spreafico

Research output: Chapter in Book/Report/Conference proceedingConference contribution


The phylogenetic development of the frontal lobe reaches maximal extension in humans where it constitutes nearly one third of the neocortex. Bundles of fibers interconnect the frontal cortex with many areas of the brain and particularly with the thalamus, basal ganglia, mesencephalon and limbic structures. Of particular importance are the interconnections among the prefrontal and the sensory association areas. Anatomical and physiological evidences indicate that the prefrontal cortex is a region of polysensory convergence. Efferent projections from the prefrontal cortex to basal ganglia and from these nuclei back to the cortex toward thalamic nuclei from the base to the loops involved in motor control. For these characteristics and for the peculiar involvement in motor representation this cortical area plays a critical role in the 'temporal structuring of behaviour'. Because of the high integrative functions and interactions btween sensory and motor representation, the prefrontal cortex may be viewed as a morphofunctional substrate of the perception-action cycle particularly devoted to intervene in the initiation and guidance of the behavioural action.

Translated title of the contributionSome morpho-functional aspects of the frontal lobe
Original languageItalian
Title of host publicationBollettino - Lega Italiana contro l'Epilessia
Number of pages6
Publication statusPublished - 1989

ASJC Scopus subject areas

  • Clinical Neurology


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