Some Physicochemical Remarks on Spontaneous Emulsification of Vitreal Tamponades

Ciro Costagliola, Francesco Semeraro, Roberto Dell'Omo, Lucio Zeppa, Gennaro Bufalo, Michele Cardone, Mario Romano, Luigi Ambrosone

Research output: Contribution to journalArticlepeer-review


The importance of gravitational instability in determining the emulsification of vitreal tamponades is discussed. Theoretical results and numerical simulations indicate that the spontaneous formation of water-silicon oil is a rare event and that the very low concentration of surface active agents cannot justify the systematic formation of emulsions. The gravitational instabilities seem to play the main role. Our theoretical results seem in agreement with the experimental evidences; furthermore they indicate a future research line for the improvement of endotamponades. Indeed, the use of biodegradable antifoam may avoid the formation of bubbles and delay the formation of emulsions.

Original languageEnglish
Article number243056
JournalBioMed Research International
Publication statusPublished - 2014

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Immunology and Microbiology(all)
  • Medicine(all)


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