Abstract
The aim of the present study was to investigate the role of nerve growth factor (NGF) and neuropeptide Y CNPY) in the higher vocal center (HVC) on singing behavior of adult male zebra finches. The results of our studies show: (a) that NGF is present in the brain of these birds and it is higher in the HVC than in the other neostriatal tissues; (b) that exogenous administration of NGF or NGF-antibody had no discernible effect on singing behavior; and (c) that NGF enhances the NPY immunoreactivity in neurons and fibers localized in HVC and other areas of the neostriatum and hippocampus whereas anti-NGF decreased NPY stained cells in the hippocampus. These studies indicate that NGF is produced in the brain of zebra finch and that it plays a role in the regulation of NPY.
Original language | English |
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Pages (from-to) | 85-92 |
Number of pages | 8 |
Journal | Behavioural Brain Research |
Volume | 101 |
Issue number | 1 |
DOIs | |
Publication status | Published - May 1999 |
Keywords
- Behavior
- Brain
- HVC
- NGF
- NPY
- Song
- Zebra finches
ASJC Scopus subject areas
- Behavioral Neuroscience