Song behavior, NGF level and NPY distribution in the brain of adult male zebra finches

Marco Fiore, Nicky S. Clayton, Luana Pistillo, Francesco Angelucci, Enrico Alleva, Luigi Aloe

Research output: Contribution to journalArticle

Abstract

The aim of the present study was to investigate the role of nerve growth factor (NGF) and neuropeptide Y CNPY) in the higher vocal center (HVC) on singing behavior of adult male zebra finches. The results of our studies show: (a) that NGF is present in the brain of these birds and it is higher in the HVC than in the other neostriatal tissues; (b) that exogenous administration of NGF or NGF-antibody had no discernible effect on singing behavior; and (c) that NGF enhances the NPY immunoreactivity in neurons and fibers localized in HVC and other areas of the neostriatum and hippocampus whereas anti-NGF decreased NPY stained cells in the hippocampus. These studies indicate that NGF is produced in the brain of zebra finch and that it plays a role in the regulation of NPY.

Original languageEnglish
Pages (from-to)85-92
Number of pages8
JournalBehavioural Brain Research
Volume101
Issue number1
DOIs
Publication statusPublished - May 1999

Keywords

  • Behavior
  • Brain
  • HVC
  • NGF
  • NPY
  • Song
  • Zebra finches

ASJC Scopus subject areas

  • Behavioral Neuroscience

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    Fiore, M., Clayton, N. S., Pistillo, L., Angelucci, F., Alleva, E., & Aloe, L. (1999). Song behavior, NGF level and NPY distribution in the brain of adult male zebra finches. Behavioural Brain Research, 101(1), 85-92. https://doi.org/10.1016/S0166-4328(98)00143-0