Sorafenib blocks tumour growth, angiogenesis and metastatic potential in preclinical models of osteosarcoma through a mechanism potentially involving the inhibition of ERK1/2, MCL-1 and ezrin pathways

Ymera Pignochino, Giovanni Grignani, Giuliana Cavalloni, Manuela Motta, Marta Tapparo, Stefania Bruno, Alessia Bottos, Loretta Gammaitoni, Giorgia Migliardi, Giovanni Camussi, Marco Alberghini, Bruno Torchio, Stefano Ferrari, Federico Bussolino, Franca Fagioli, Piero Picci, Massimo Aglietta

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Medicine & Life Sciences