SPA therapy of upper respiratory tract inflammations

D. Passali, E. De Corso, S. Platzgummer, C. Streitberger, S. Lo Cunsolo, G. Nappi, G. C. Passali, L. Bellussi

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

The upper airway respiratory diseases (i.e. common cold, allergic rhinitis, nonallergic/vasomotor rhinitis, acute and chronic rhinosinusitis and nasal polyposis) in which nasal congestion is a common symptom are often undertreated due to the frequent inadequate efficacy and safety concern with current therapies. In scientific literature, few studies seem to support the hypothesis that nasal inhalatory treatment with thermal water promotes the improvement of nasal symptoms, even if the mechanisms by which the improvement from SPA therapy can be expected remain debated. A prospective comparative study with a pre-post design has been performed consecutively enrolling 33 (males 70 %) patients of both genders older than 12 years of age, affected by chronic sinonasal inflammation. All patients underwent a 14-days course of radioactive water warm vapour inhalations followed by nasal aerosol of the same thermal water 10 min each once/day at Merano Therme. At the beginning and end of the study, in all the subjects, nasal function evaluation by active anterior rhinomanometry, mucociliary transport time (MCTt) determination and nasal cytology were performed. After the inhalatory treatment, the mucociliary function was improved and the pathologic mucociliary transport times recorded at the beginning of the study being significantly reduced to physiologic ones. Besides, before treatment, the cytologic picture showed an inflammatory cell infiltration (eosinophils, neutrophils with/without bacteria, mast cells) in 37 % of patients; after therapy in 66 % of these patients, the rhinocytogram was normal. Our results suggest, according to the literature data, that SPA therapy with radioactive water could represent an alternative choice in chronic inflammatory diseases of the upper airways, nonresponsive to pharmacological therapy.

Original languageEnglish
Pages (from-to)565-570
Number of pages6
JournalEuropean Archives of Oto-Rhino-Laryngology
Volume270
Issue number2
DOIs
Publication statusPublished - Feb 2013

Fingerprint

Respiratory System
Nose
Inflammation
Mucociliary Clearance
Therapeutics
Water
Hot Temperature
Vasomotor Rhinitis
Rhinomanometry
Literature
Nasal Sprays
Common Cold
Neutrophil Infiltration
Steam
Eosinophils
Mast Cells
Inhalation
Cell Biology
Chronic Disease
Prospective Studies

Keywords

  • Sinunasal pathology
  • SPA therapy
  • URTI

ASJC Scopus subject areas

  • Otorhinolaryngology

Cite this

Passali, D., De Corso, E., Platzgummer, S., Streitberger, C., Lo Cunsolo, S., Nappi, G., ... Bellussi, L. (2013). SPA therapy of upper respiratory tract inflammations. European Archives of Oto-Rhino-Laryngology, 270(2), 565-570. https://doi.org/10.1007/s00405-012-2024-5

SPA therapy of upper respiratory tract inflammations. / Passali, D.; De Corso, E.; Platzgummer, S.; Streitberger, C.; Lo Cunsolo, S.; Nappi, G.; Passali, G. C.; Bellussi, L.

In: European Archives of Oto-Rhino-Laryngology, Vol. 270, No. 2, 02.2013, p. 565-570.

Research output: Contribution to journalArticle

Passali, D, De Corso, E, Platzgummer, S, Streitberger, C, Lo Cunsolo, S, Nappi, G, Passali, GC & Bellussi, L 2013, 'SPA therapy of upper respiratory tract inflammations', European Archives of Oto-Rhino-Laryngology, vol. 270, no. 2, pp. 565-570. https://doi.org/10.1007/s00405-012-2024-5
Passali D, De Corso E, Platzgummer S, Streitberger C, Lo Cunsolo S, Nappi G et al. SPA therapy of upper respiratory tract inflammations. European Archives of Oto-Rhino-Laryngology. 2013 Feb;270(2):565-570. https://doi.org/10.1007/s00405-012-2024-5
Passali, D. ; De Corso, E. ; Platzgummer, S. ; Streitberger, C. ; Lo Cunsolo, S. ; Nappi, G. ; Passali, G. C. ; Bellussi, L. / SPA therapy of upper respiratory tract inflammations. In: European Archives of Oto-Rhino-Laryngology. 2013 ; Vol. 270, No. 2. pp. 565-570.
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