The electroclinical findings in 9 infants presenting with clusters of 'spasms' with a typical ictal EEG pattern, but without interictal hypsarrythmia are reported. In 7 patients an evident neurological impairment preceeded the spasms onset. The clinical course was severe in all cases. The clinical features and the interictal EEG pattern suggest that in our patients the pathophysiological mechanism of ictal phenomena of 'spasms' is linked to a particular developmental stage of the brain, independently from the etiological factors. The opinion of the authors is that this type of clinical picture must be kept distinct from 'West syndrome' to avoid the risk of including too many heterogeneous pathological conditions under the same nosological heading.
|Translated title of the contribution||Spasms without hypsarrythmic EEG pattern: Electroclinical features in 9 newly diagnosed patients|
|Number of pages||3|
|Journal||Bollettino - Lega Italiana contro l'Epilessia|
|Publication status||Published - 1990|
ASJC Scopus subject areas
- Clinical Neurology