Spatial working memory in asymptomatic HIV-infected subjects

Barbara Grassi, Giacomo Garghentini, Arturo Campana, Elena Grassi, Sara Bertelli, Paola Cinque, Mara Epifani, Adriano Lazzarin, Silvio Scarone

Research output: Contribution to journalArticlepeer-review


Many clinical and research findings converge to indicate that frontal lobe, basal ganglia, and related neuronal connections are primarily involved in human immunodeficiency virus (HIV) infection; frontal lobe, mainly the prefrontal cortex, has a specialised role in working memory processes. This study focused on neuropsychological evaluation of the spatial component of working memory in a sample of 34 asymptomatic HIV-infected subjects as compared with 34 age- and sex-matched seronegative control subjects. A computer-administered test assessing spatial working memory was used for the neuropsychological evaluation. The findings did not show any spatial working memory impairment during the asymptomatic phase of HIV infection.

Original languageEnglish
Pages (from-to)387-391
Number of pages5
JournalJournal of Neuropsychiatry and Clinical Neurosciences
Issue number3
Publication statusPublished - Jun 1999

ASJC Scopus subject areas

  • Neuropsychology and Physiological Psychology
  • Neuroscience(all)


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