Abstract
The effectiveness of various symptomatic drugs has been documented by controlled clinical trials. A review of the data from the literature has identified a group of substances that proved significantly better than placebo in at least two controlled trials. These drugs include triptans, ergots, non-steroidal anti-inflammatory drugs and anti-emetics. With the exception of ergotamine, which is ineffective or may even worsen nausea, all of them possess both analgesic and anti-emetic effects, provided that they are used according to the proper dosage and administration route. The choice of the appropriate drug, formulation and route of administration is a crucial step in the therapeutic approach of migraine. This choice must be guided by the clinical characteristics of the migraine attack, co-morbid or associated conditions, drug-related factors and patient' preferences.
Original language | Italian |
---|---|
Pages (from-to) | 69-83 |
Number of pages | 15 |
Journal | Confinia Cephalalgica |
Volume | 9 |
Issue number | 2 |
Publication status | Published - 2000 |
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ASJC Scopus subject areas
- Clinical Neurology
Cite this
Farmaci sintomatici specifici e aspecifici per il trattamento acuto dell'attacco emicranico : Nuove opzioni terapeutiche. / Nappi, G.; Sances, G.; Tassorelli, C.; Ambrosio, R.; Sandrini, G.
In: Confinia Cephalalgica, Vol. 9, No. 2, 2000, p. 69-83.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Farmaci sintomatici specifici e aspecifici per il trattamento acuto dell'attacco emicranico
T2 - Nuove opzioni terapeutiche
AU - Nappi, G.
AU - Sances, G.
AU - Tassorelli, C.
AU - Ambrosio, R.
AU - Sandrini, G.
PY - 2000
Y1 - 2000
N2 - The effectiveness of various symptomatic drugs has been documented by controlled clinical trials. A review of the data from the literature has identified a group of substances that proved significantly better than placebo in at least two controlled trials. These drugs include triptans, ergots, non-steroidal anti-inflammatory drugs and anti-emetics. With the exception of ergotamine, which is ineffective or may even worsen nausea, all of them possess both analgesic and anti-emetic effects, provided that they are used according to the proper dosage and administration route. The choice of the appropriate drug, formulation and route of administration is a crucial step in the therapeutic approach of migraine. This choice must be guided by the clinical characteristics of the migraine attack, co-morbid or associated conditions, drug-related factors and patient' preferences.
AB - The effectiveness of various symptomatic drugs has been documented by controlled clinical trials. A review of the data from the literature has identified a group of substances that proved significantly better than placebo in at least two controlled trials. These drugs include triptans, ergots, non-steroidal anti-inflammatory drugs and anti-emetics. With the exception of ergotamine, which is ineffective or may even worsen nausea, all of them possess both analgesic and anti-emetic effects, provided that they are used according to the proper dosage and administration route. The choice of the appropriate drug, formulation and route of administration is a crucial step in the therapeutic approach of migraine. This choice must be guided by the clinical characteristics of the migraine attack, co-morbid or associated conditions, drug-related factors and patient' preferences.
KW - Analgesics
KW - Antiemetics
KW - Combination products
KW - Ergot-derivatives
KW - Migraine
KW - Triptans
UR - http://www.scopus.com/inward/record.url?scp=0033829579&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0033829579&partnerID=8YFLogxK
M3 - Articolo
AN - SCOPUS:0033829579
VL - 9
SP - 69
EP - 83
JO - Confinia Cephalalgica
JF - Confinia Cephalalgica
SN - 1122-0279
IS - 2
ER -