Specific desensitizing treatment in allergy to iodine-containing contrast media: Observation in one patient

G. Patriarca, A. Venuti, D. Schiavino, A. Romano

Research output: Contribution to journalArticlepeer-review


A case of successful desensitizing treatment in a patient presenting allergic reaction to iodine containing contrast media inasmuch as no similar accounts have been published. On the basis of previous findings following desensitizing treatment for drug allergy such as penicillin, synthetic corticotropin and insulin (unpublished data) immunotherapy in drug allergy should not present particular problems provided certain conditions are taken into consideration. Treatment should be performed by highly qualified personnel and preferably on patients during hospitalization. It is advisable to commence treatment employing the minimum dose, if injected intradermally, capable of inducing an erythematous wheal reaction. It is preferable to commence treatment by the intradermal route, proceeding, in the specific case of allergy to contrast media, with i.v. administration. During the final stages of treatment it may be useful to add an antihistaminic drug. The need to proceed with maintenance treatment should be evaluated according to the particular circumstances (e.g., corticotropins in asthmatic patients, insulin in diabetics). Hematochemical studies should be performed throughout treatment in order to reveal any possible signs of toxicity (which were not detected either in the present, or previous, observations).

Original languageEnglish
Pages (from-to)200-202
Number of pages3
JournalAnnals of Allergy
Issue number3
Publication statusPublished - 1978

ASJC Scopus subject areas

  • Immunology and Allergy


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