Specific desensitizing treatment in drug allergy

G. Patriarca, A. Venuti, D. Schiavino, A. Romano

Research output: Contribution to journalArticlepeer-review


Fourteen patients with allergy to drugs (4 to synthetic corticotrophin, 3 to insulin, 4 to pyramidon, 2 to penicillin, and 1 to iodine-containing contrast media) were submitted to specific densensitizing treatment using graduated doses of the drug. Therapy was completely successful in 11 of 14 cases: in one case, the authors were forced to suspend treatment because the patient allergic to pyramidon had become pregnant; in other cases (allergic to corticotrophin and to penicillin) the treatment was suspended because of severe adverse reactions. On the basis of the present findings, immunotherapy in drug allergy is possible and should not present any special problems: it is necessary that the treatment be carried out by highly qualified staff and preferably on hospitalized patients.

Original languageEnglish
Pages (from-to)373-376
Number of pages4
JournalAllergologia et Immunopathologia
Issue number5
Publication statusPublished - 1979

ASJC Scopus subject areas

  • Immunology and Allergy


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