The present study deals with the suppressor activity of adherent cells on the specifically tumor-induced LIF production in patients with larngeal cancer. The specific LIF production was evaluated in 20 patients before and after the removal of adherent cell according to Mantovani's technique. The results can be summarized as follows: I) A specific LIF production was present in 12 out of 20 cases. II) The removal of adherent cells either increased the LIF production in positive cases or turned 40% of the previously negative cases into positive cases. These data seem to indicate the presence in laryngeal cancer patients of a suppressor activity of the immune mechanism by adherent cells also for the LIF system and confirm the results previously obtained in Mixed Leukocyte Culture by Berlinger (1976).
|Number of pages||2|
|Journal||IRCS Medical Science|
|Publication status||Published - 1982|
ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)