Abstract
When the transketolase-defective and D-ribose-producing Bacillus subtilis strain ATCC 21951 was cultured in a medium provided with certain organic acids, a significantly enhanced D-ribose titre was obtained, while the production of acetoin and 2,3-butanediol drastically decreased. Although the biochemical background of this phenomenon is not completely understood, it makes D-ribose synthesis more efficient and cheaper, the latter due to an easier recovery of D-ribose from the fermentation medium.
| Original language | English |
|---|---|
| Pages (from-to) | 311-315 |
| Number of pages | 5 |
| Journal | Journal of Chemical Technology and Biotechnology |
| Volume | 70 |
| Issue number | 3 |
| DOIs | |
| Publication status | Published - Nov 1997 |
Keywords
- Bacillus subtilis
- D-ribose
- Organic acid
- Pentose phosphate cycle
- Transketolase
ASJC Scopus subject areas
- Biotechnology
- Chemical Engineering(all)
- Bioengineering
- Chemistry(all)