Spermatic Cord Sarcoma: A 20-Year Single-Institution Experience

Massimo Iafrate, Giovanni Motterle, Carlotta Zaborra, Niccolò Leone, Tommaso Prayer-Galetti, Filiberto Zattoni, Andrea Guttilla, Rocco Cappellesso, Angelo Paolo Dei Tos, Carlo Riccardo Rossi, Paolo Del Fiore, Marco Rastrelli, Simone Mocellin

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Introduction: Spermatic cord sarcomas represent a rare genitourinary malignancy with a challenging diagnostic and therapeutic pathway. Different histotypes have been described and prognostic factors remain poorly defined due to the paucity of data presented in literature. Methods: Retrospective chart review of 22 adult patients treated for spermatic cord sarcoma in a single institution in the last 20 years was performed. Clinicopathological characteristics of the tumors were collected with primary and subsequent treatment. Survival analysis was performed in order to identify prognostic factors of disease-specific survival. Results: The median age at diagnosis was 68 years (58–78), the most common histotype was liposarcoma (14/22), and most patients (63.6%) were found to have positive surgical margins after surgery. The 5-year cancer specific survival was 91.3%. Grading (p = 0.480), histotype (p = 0.327), and type of intervention (p = 0.732) were not associated with survival. All patients dead of disease had positive surgical margins (p = 0.172). Conclusion: We report a good prognosis at 5 years. Wide radical resection remains the first and probably the most important step; thus, according also to literature, negative surgical margins should be aimed.

Original languageEnglish
Article number566408
Number of pages6
JournalFrontiers in Surgery
Publication statusPublished - Nov 17 2020


  • paratesticular sarcoma
  • soft tissue sarcoma
  • spermatic cord
  • spermatic cord sarcoma
  • treatment
  • urologic sarcoma

ASJC Scopus subject areas

  • Surgery


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