Spinal cord lesions shrink peripersonal space around the feet, passive mobilization of paraplegic limbs restores it

Michele Scandola, Salvatore Maria Aglioti, Claudio Bonente, Renato Avesani, Valentina Moro

Research output: Contribution to journalArticle

Abstract

Peripersonal space (PPS) is the space surrounding us within which we interact with objects. PPS may be modulated by actions (e.g. when using tools) or sense of ownership (e.g. over a rubber hand). Indeed, intense and/or prolonged use of a tool may induce a sense of ownership over it. Conversely, inducing ownership over a rubber hand may activate brain regions involved in motor control. However, the extent to which PPS is modulated by action-dependent or ownership-dependent mechanisms remains unclear. Here, we explored the PPS around the feet and the sense of ownership over lower limbs in people with Paraplegia following Complete spinal cord Lesions (PCL) and in healthy subjects. PCL people can move their upper body but have lost all sensory-motor functions in their lower body (e.g. lower limbs). We tested whether PPS alterations reflect the topographical representations of various body parts. We found that the PPS around the feet was impaired in PCL who however had a normal representation of the PPS around the hands. Significantly, passive mobilization of paraplegic limbs restored the PPS around the feet suggesting that activating action representations in PCL brings about short-term changes of PPS that may thus be more plastic than previously believed.

Original languageEnglish
Article number24126
JournalScientific Reports
Volume6
DOIs
Publication statusPublished - Apr 6 2016

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Ownership
Foot
Spinal Cord
Extremities
Hand
Rubber
Lower Extremity
Paraplegia
Human Body
Plastics
Healthy Volunteers
Brain

ASJC Scopus subject areas

  • General

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Spinal cord lesions shrink peripersonal space around the feet, passive mobilization of paraplegic limbs restores it. / Scandola, Michele; Aglioti, Salvatore Maria; Bonente, Claudio; Avesani, Renato; Moro, Valentina.

In: Scientific Reports, Vol. 6, 24126, 06.04.2016.

Research output: Contribution to journalArticle

Scandola, Michele ; Aglioti, Salvatore Maria ; Bonente, Claudio ; Avesani, Renato ; Moro, Valentina. / Spinal cord lesions shrink peripersonal space around the feet, passive mobilization of paraplegic limbs restores it. In: Scientific Reports. 2016 ; Vol. 6.
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