Sarcoidosis is a multisystemic granulomatosis disorder of unknown cause, characterized by enhanced cellular immune processes at the sites of disease activity. Neurosarcoidosis develops in 5% of patients with systemic sarcoidosis. Some one third of patients with neurosarcoidosis have refractory illness that is associated with considerable morbidity and potential mortality. Although spinal cord involvement is rare, it may cause severe neurological complications. We report the case of a fourty-seven year-old woman who developed pulmonary and spinal sarcoidosis. Neurological symptoms (progressive paraparesis) represented the initial manifestation of the disease. Serum Angiotensin-Converting Enzyme (ACE) level was normal. Clinical, diagnostic and therapeutic aspects during two years of follow-up are analised.
|Number of pages||1|
|Journal||Italian Journal of Neurological Sciences|
|Publication status||Published - 1997|
ASJC Scopus subject areas
- Clinical Neurology