Spinal sympathetic reflexes in the cat and the pathogenesis of arterial hypertension.

A. Malliani; F. Lombardi; M. Pagani; G. Recordati; P. J. Schwartz

Spinal sympathetic reflexes in the cat and the pathogenesis of arterial hypertension.

A. Malliani, F. Lombardi, M. Pagani, G. Recordati, P. J. Schwartz

Research output: Contribution to journal › Article › peer-review

Abstract

1. In vagotomized anaesthetized cats with both common carotid arteries occluded, stretch of the thoracic aorta induced reflex increases in arterial blood pressure, heart rate and left ventricular dP/dtmax. Similar responses were obtained in cats with spinal transection at the level of the first cervical nerve roots. 2. The hypothesis is advanced that sympathetic excitatory reflexes may contribute to the maintenance of hypertension through positive feedback.

Original language	English
Journal	Clinical science and molecular medicine. Supplement
Volume	2
Publication status	Published - Jun 1975

ASJC Scopus subject areas

Medicine(all)

Cite this

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title = "Spinal sympathetic reflexes in the cat and the pathogenesis of arterial hypertension.",

abstract = "1. In vagotomized anaesthetized cats with both common carotid arteries occluded, stretch of the thoracic aorta induced reflex increases in arterial blood pressure, heart rate and left ventricular dP/dtmax. Similar responses were obtained in cats with spinal transection at the level of the first cervical nerve roots. 2. The hypothesis is advanced that sympathetic excitatory reflexes may contribute to the maintenance of hypertension through positive feedback.",

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AU - Malliani, A.

AU - Lombardi, F.

AU - Pagani, M.

AU - Recordati, G.

AU - Schwartz, P. J.

PY - 1975/6

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N2 - 1. In vagotomized anaesthetized cats with both common carotid arteries occluded, stretch of the thoracic aorta induced reflex increases in arterial blood pressure, heart rate and left ventricular dP/dtmax. Similar responses were obtained in cats with spinal transection at the level of the first cervical nerve roots. 2. The hypothesis is advanced that sympathetic excitatory reflexes may contribute to the maintenance of hypertension through positive feedback.

AB - 1. In vagotomized anaesthetized cats with both common carotid arteries occluded, stretch of the thoracic aorta induced reflex increases in arterial blood pressure, heart rate and left ventricular dP/dtmax. Similar responses were obtained in cats with spinal transection at the level of the first cervical nerve roots. 2. The hypothesis is advanced that sympathetic excitatory reflexes may contribute to the maintenance of hypertension through positive feedback.

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JO - Clinical science and molecular medicine. Supplement

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Spinal sympathetic reflexes in the cat and the pathogenesis of arterial hypertension.

Abstract

ASJC Scopus subject areas

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