Spindle cell neuroendocrine carcinoma of the lung: Report of a case with fine needle aspiration cytology and differential diagnostic considerations

Franco Fulciniti, Franca La Vecchia, Maria Staiano, Fabiana Tatangelo, Vincenzo De Rosa, Gaetano Rocco, Antonello La Rocca, Gerardo Botti

Research output: Contribution to journalArticle

Abstract

Background: Spindle cell neuroendocrine carcinomas of the lung may be frequently observed on fine needle cytology (FNC) samples and often pose stimulating differential diagnostic problems. Case: The cytopathologic findings from FNC performed on a long-standing coin lesion of the lung in a 54-year-old woman were analyzed in view of the data and long clinical history. Conclusion A final diagnosis of low grade spindle cell neuroendocrine carcinoma was reached by combining cytopathologic and immunocytochemical information. The main lesions considered in the differential diagnosis were intrapulmonary inflammatory myofibroblastic tumor (fibrohistiocytic variant) and spindle cell thymoma.

Original languageEnglish
Pages (from-to)227-230
Number of pages4
JournalActa Cytologica
Volume51
Issue number2
Publication statusPublished - 2007

Keywords

  • Aspiration biopsy, fine-needle
  • Carcinoma, neuroendocrine
  • Carcinoma, spindle-cell
  • Pulmonary coin lesions

ASJC Scopus subject areas

  • Anatomy
  • Cell Biology
  • Histology

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