Spinocerebellar Purkinje cells and rat forelimb postures: A direction- dependent activity

Genoveffa Giaquinta, Antonino Casabona, Maria Stella Valle, Gianfranco Bosco, Vincenzo Perciavalle

Research output: Contribution to journalArticle

Abstract

On anesthetized adult rats, we examined the possibility that the discharges of spinocerebellar Purkinje cells (PCs) are modulated by passive limb positioning. The rat forelimb was passively placed in four different sagittal positions while the simple spike spontaneous activity of single PCs was recorded; recordings started 5 s after the reaching of the posture and the forelimb remained at each position for at least 30 s. Although the activity of the PCs did not reflect the forelimb position, it showed hysteresis that depended in a cosine fashion on the direction of the preceding movement. This implies that the directional sensitivity of spinocerebellar PCs is persistent, since the activity levels were almost constant throughout the recording time.

Original languageEnglish
Pages (from-to)81-84
Number of pages4
JournalNeuroscience Letters
Volume245
Issue number2
DOIs
Publication statusPublished - Apr 3 1998

Keywords

  • Cerebellum
  • Limb posture
  • Neuronal encoding
  • Simple spike activity

ASJC Scopus subject areas

  • Neuroscience(all)

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