Spiral MR fingerprinting at 7T with simultaneous B1 estimation

Guido Buonincontri, Rolf F. Schulte, Mirco Cosottini, Michela Tosetti

Research output: Contribution to journalArticle

Abstract

Magnetic resonance fingerprinting is an efficient, new approach for quantitative imaging with MR. We aimed to extend this technique to cases with B1. + inhomogeneities within the imaging volume.Previous approaches have used abrupt changes in flip angles to estimate the B1. + field simultaneously with T1 and T2, using a Cartesian approach in a small-animal scanner at 4.7. T. Here, we evaluated whether a similar approach would be suitable for imaging human brains using spiral readouts with a 7. T scanner.We found that our modified scheme could significantly reduce the adverse effects of B1. + inhomogeneities even in extreme cases, reducing both the bias and the variance in T2 estimations by an order of magnitude when compared to literature methods. Acquisitions used less than 1.5. W/kg SAR and could be performed in 12. s per slice.In conclusion, our approach can be used to perform quantitative imaging of the brain at 7. T in a short time, simultaneously estimating the B1. + profile.

Original languageEnglish
JournalMagnetic Resonance Imaging
DOIs
Publication statusAccepted/In press - Sep 15 2016

Keywords

  • B1+
  • MR fingerprinting
  • Spiral
  • T1
  • T2

ASJC Scopus subject areas

  • Biophysics
  • Biomedical Engineering
  • Radiology Nuclear Medicine and imaging

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