TY - JOUR
T1 - Spirometry
T2 - Predicting Risk and Outcome
AU - Brunelli, Alessandro
AU - Rocco, Gaetano
PY - 2008/2
Y1 - 2008/2
N2 - For decades, surgery has been the mainstay of treatment in early stage lung cancer, as well as complex infectious conditions of the lung. Concomitantly, forced expiratory volume (FEV1) alone has been the discriminating parameter of surgical eligibility. Still, the limitations of FEV1 have emerged in published literature, and so carbon monoxide diffusing capacity (DLCO) has been suggested as a complementary parameter, to be introduced along with the concept of defining numeric values corresponding to the predicted postoperative figures of FEV1 and DLCO. However, recent evidence argues against the predicting ability of postoperative FEV1 and DLCO, especially in the immediate postoperative period and in patients with severe airflow limitation.
AB - For decades, surgery has been the mainstay of treatment in early stage lung cancer, as well as complex infectious conditions of the lung. Concomitantly, forced expiratory volume (FEV1) alone has been the discriminating parameter of surgical eligibility. Still, the limitations of FEV1 have emerged in published literature, and so carbon monoxide diffusing capacity (DLCO) has been suggested as a complementary parameter, to be introduced along with the concept of defining numeric values corresponding to the predicted postoperative figures of FEV1 and DLCO. However, recent evidence argues against the predicting ability of postoperative FEV1 and DLCO, especially in the immediate postoperative period and in patients with severe airflow limitation.
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U2 - 10.1016/j.thorsurg.2007.10.007
DO - 10.1016/j.thorsurg.2007.10.007
M3 - Article
C2 - 18402196
AN - SCOPUS:38749097759
VL - 18
SP - 1
EP - 8
JO - Thoracic Surgery Clinics
JF - Thoracic Surgery Clinics
SN - 1547-4127
IS - 1
ER -