Abstract
Three cases of Spitz nevus of the tongue associated with pseudoepitheliomatous hyperplasia are reported: two occurring in children and one in an adult. The location at an unusual site and the complex pattern resulting from the intimate admixture of the neoplastic melanocytic component and the hyperplastic keratinocytic component led in each case to consider diagnoses such as malignant melanoma and invasive squamous cell carcinoma. Staining for S-100 protein and keratin was useful to identify and separate the two components. Spitz nevus of the tongue carries some intriguing similarities with granular cell tumor, suggesting a possible histogenetic and pathogenetic relationship.
| Original language | English |
|---|---|
| Pages (from-to) | 774-777 |
| Number of pages | 4 |
| Journal | American Journal of Surgical Pathology |
| Volume | 26 |
| Issue number | 6 |
| DOIs | |
| Publication status | Published - 2002 |
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Keywords
- Pseudoepitheliomatous hyperplasia
- Spitz nevus
- Tongue
ASJC Scopus subject areas
- Anatomy
- Pathology and Forensic Medicine
Cite this
Spitz nevus of the tongue with pseudoepitheliomatous hyperplasia : Report of three cases of a pseudomalignant condition. / Dorji, Tshering; Cavazza, Alberto; Nappi, Oscar; Rosai, Juan.
In: American Journal of Surgical Pathology, Vol. 26, No. 6, 2002, p. 774-777.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Spitz nevus of the tongue with pseudoepitheliomatous hyperplasia
T2 - Report of three cases of a pseudomalignant condition
AU - Dorji, Tshering
AU - Cavazza, Alberto
AU - Nappi, Oscar
AU - Rosai, Juan
PY - 2002
Y1 - 2002
N2 - Three cases of Spitz nevus of the tongue associated with pseudoepitheliomatous hyperplasia are reported: two occurring in children and one in an adult. The location at an unusual site and the complex pattern resulting from the intimate admixture of the neoplastic melanocytic component and the hyperplastic keratinocytic component led in each case to consider diagnoses such as malignant melanoma and invasive squamous cell carcinoma. Staining for S-100 protein and keratin was useful to identify and separate the two components. Spitz nevus of the tongue carries some intriguing similarities with granular cell tumor, suggesting a possible histogenetic and pathogenetic relationship.
AB - Three cases of Spitz nevus of the tongue associated with pseudoepitheliomatous hyperplasia are reported: two occurring in children and one in an adult. The location at an unusual site and the complex pattern resulting from the intimate admixture of the neoplastic melanocytic component and the hyperplastic keratinocytic component led in each case to consider diagnoses such as malignant melanoma and invasive squamous cell carcinoma. Staining for S-100 protein and keratin was useful to identify and separate the two components. Spitz nevus of the tongue carries some intriguing similarities with granular cell tumor, suggesting a possible histogenetic and pathogenetic relationship.
KW - Pseudoepitheliomatous hyperplasia
KW - Spitz nevus
KW - Tongue
UR - http://www.scopus.com/inward/record.url?scp=0036100403&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0036100403&partnerID=8YFLogxK
U2 - 10.1097/00000478-200206000-00011
DO - 10.1097/00000478-200206000-00011
M3 - Article
C2 - 12023582
AN - SCOPUS:0036100403
VL - 26
SP - 774
EP - 777
JO - American Journal of Surgical Pathology
JF - American Journal of Surgical Pathology
SN - 0147-5185
IS - 6
ER -