Abstract
Spitz nevus can clinically present either in the classical (reddish pink) or the pigmented (brownish black) variant. Dermoscopy demonstrates that the pigmented variant is much more common than the classical variant; however, none of these show dermoscopic patterns clearly distinguishable from melanoma. Even histopathologically, a clear-cut differentiation between benign and malignant spitzoid neoplasms is often difficult, so that intermediate diagnostic categories (atypical Spitz nevus and Spitz tumor) are admitted. Because of these difficulties in clinical and histopathologic evaluation, surgical excision is recommended for clinically atypical spitzoid lesions of childhood and for all spitzoid lesions of adulthood.
| Original language | English |
|---|---|
| Pages (from-to) | 589-598 |
| Number of pages | 10 |
| Journal | Dermatologic Clinics |
| Volume | 31 |
| Issue number | 4 |
| DOIs | |
| Publication status | Published - Oct 2013 |
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Keywords
- Atypical Spitz nevus
- Dermoscopy
- Histopathology
- Spitz nevus
- Spitz tumor
- Spitzoid melanoma
ASJC Scopus subject areas
- Dermatology
Cite this
Spitz Nevus, Spitz Tumor, and Spitzoid Melanoma. A Comprehensive Clinicopathologic Overview. / Ferrara, Gerardo; Gianotti, Raffaele; Cavicchini, Stefano; Salviato, Tiziana; Zalaudek, Iris; Argenziano, Giuseppe.
In: Dermatologic Clinics, Vol. 31, No. 4, 10.2013, p. 589-598.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Spitz Nevus, Spitz Tumor, and Spitzoid Melanoma. A Comprehensive Clinicopathologic Overview.
AU - Ferrara, Gerardo
AU - Gianotti, Raffaele
AU - Cavicchini, Stefano
AU - Salviato, Tiziana
AU - Zalaudek, Iris
AU - Argenziano, Giuseppe
PY - 2013/10
Y1 - 2013/10
N2 - Spitz nevus can clinically present either in the classical (reddish pink) or the pigmented (brownish black) variant. Dermoscopy demonstrates that the pigmented variant is much more common than the classical variant; however, none of these show dermoscopic patterns clearly distinguishable from melanoma. Even histopathologically, a clear-cut differentiation between benign and malignant spitzoid neoplasms is often difficult, so that intermediate diagnostic categories (atypical Spitz nevus and Spitz tumor) are admitted. Because of these difficulties in clinical and histopathologic evaluation, surgical excision is recommended for clinically atypical spitzoid lesions of childhood and for all spitzoid lesions of adulthood.
AB - Spitz nevus can clinically present either in the classical (reddish pink) or the pigmented (brownish black) variant. Dermoscopy demonstrates that the pigmented variant is much more common than the classical variant; however, none of these show dermoscopic patterns clearly distinguishable from melanoma. Even histopathologically, a clear-cut differentiation between benign and malignant spitzoid neoplasms is often difficult, so that intermediate diagnostic categories (atypical Spitz nevus and Spitz tumor) are admitted. Because of these difficulties in clinical and histopathologic evaluation, surgical excision is recommended for clinically atypical spitzoid lesions of childhood and for all spitzoid lesions of adulthood.
KW - Atypical Spitz nevus
KW - Dermoscopy
KW - Histopathology
KW - Spitz nevus
KW - Spitz tumor
KW - Spitzoid melanoma
UR - http://www.scopus.com/inward/record.url?scp=84884683220&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84884683220&partnerID=8YFLogxK
U2 - 10.1016/j.det.2013.06.012
DO - 10.1016/j.det.2013.06.012
M3 - Article
C2 - 24075547
AN - SCOPUS:84884683220
VL - 31
SP - 589
EP - 598
JO - Dermatologic Clinics
JF - Dermatologic Clinics
SN - 0733-8635
IS - 4
ER -