Splenectomy during primary and secondary cytoreductive surgery for epithelial ovarian carcinoma

C. Scarabelli, A. Gallo, E. Campagnutta, A. Carbone

Research output: Contribution to journalArticlepeer-review


Splenectomy is occasionally indicated to achieve optimal cytoreduction during surgery for epithelial ovarian cancer. Between January 1989 and December 1996, 40 epithelial ovarian cancer patients underwent splenectomy: 14 patients during primary surgery and 26 during secondary cytoreductive surgery. Splenectomy was performed for tumor reduction in 34 patients (85%) and for iatrogenic injury in six patients (15%). The spleen was removed because of parenchymal splenic metastases in nine patients (22.5%), significant hilar and/or capsular disease in 10 patients (25%), and perisplenic disease in 15 patients (37.5%). The histopathological diagnosis of the resected spleens showed microscopic hilar disease in four patients who had the spleen removed because of iatrogenic injury and no disease in only two patients. Splenectomy could be carried out with an acceptable morbidity. Left-sided pleural effusion was the most frequent complication. The estimated two-year survival rate for patients who underwent splenectomy during primary surgery with no residual disease and 1 year) recurrent disease.

Original languageEnglish
Pages (from-to)215-221
Number of pages7
JournalInternational Journal of Gynecological Cancer
Issue number3
Publication statusPublished - 1998


  • Cytoreductive surgery
  • Ovarian carcinoma
  • Splenectomy

ASJC Scopus subject areas

  • Cancer Research
  • Obstetrics and Gynaecology
  • Oncology


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