Splenic autotransplantation after splenectomy: Tuftsin activity correlates with residual splenic function

G. Zoli, G. R. Corazza, G. D'Amato, R. Bartoli, F. Baldoni, G. Gasbarrini

Research output: Contribution to journalArticlepeer-review

Abstract

This study set out to determine the relationship between splenic function (as assessed by the percentage of pitted red cells) and tuftsin activity, and to confirm the return of effective splenic function after splenectomy for trauma. Twenty-three patients (13 men) took part. Ten of mean age 48.5 (range 30-74) years had had the spleen removed for traumatic rupture and 13 of mean age 49.7 (range 23-66) years had undergone elective splenectomy. At the time of the study all patients had had the spleen removed a minimum of 1 year previously (mean 6.1 (range 1-15) years). Fifty healthy volunteers matched for sex and age were also studied. In each subject, residual splenic function was evaluated by counting the percentage of pitted red cells. Tuftsin activity was also determined. A highly significant negative correlation was found between pitted red cell percentage and tuftsin activity (r(S) = -0.80, P

Original languageEnglish
Pages (from-to)716-718
Number of pages3
JournalBritish Journal of Surgery
Volume81
Issue number5
DOIs
Publication statusPublished - 1994

ASJC Scopus subject areas

  • Surgery

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