TY - JOUR
T1 - Spontaneous confabulations in amnestic-mild cognitive impairment due to Alzheimer’s disease
T2 - a new (yet old) atypical variant?
AU - Abbate, Carlo
AU - Trimarchi, Pietro Davide
AU - Rotondo, Emanuela
AU - Inglese, Silvia
AU - Nicolini, Paola
AU - Rossi, Paolo Dionigi
AU - Arosio, Beatrice
AU - Mari, Daniela
PY - 2016
Y1 - 2016
N2 - Confabulation may be present in Alzheimer’s disease (AD), but usually it is not a primary feature of either its typical or atypical variants. In this report, we describe the case of an AD patient who showed an unusual and enduring neuropsychiatric phenotype characterized by early and prominent spontaneous confabulation. Surprisingly, such atypical AD presentation bears a striking resemblance to presbyophrenia, a subtype of dementia which was described at the beginning of the twentieth century and then sank into oblivion. In discussion, we speculate on the “return” of presbyophrenia as an unrecognized neuropsychiatric variant of AD and its possible neuroanatomical substrates.
AB - Confabulation may be present in Alzheimer’s disease (AD), but usually it is not a primary feature of either its typical or atypical variants. In this report, we describe the case of an AD patient who showed an unusual and enduring neuropsychiatric phenotype characterized by early and prominent spontaneous confabulation. Surprisingly, such atypical AD presentation bears a striking resemblance to presbyophrenia, a subtype of dementia which was described at the beginning of the twentieth century and then sank into oblivion. In discussion, we speculate on the “return” of presbyophrenia as an unrecognized neuropsychiatric variant of AD and its possible neuroanatomical substrates.
KW - (Spontaneous) confabulations
KW - Alzheimer’s disease (AD)
KW - atypical variant AD
KW - Mild Cognitive Impairment (MCI)
KW - presbyophrenia
UR - http://www.scopus.com/inward/record.url?scp=84990236818&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84990236818&partnerID=8YFLogxK
U2 - 10.1080/13554794.2016.1239743
DO - 10.1080/13554794.2016.1239743
M3 - Article
AN - SCOPUS:84990236818
VL - 22
SP - 451
EP - 460
JO - Neurocase
JF - Neurocase
SN - 1355-4794
IS - 5
ER -