Spontaneous CSF rhinorrhea through the lamina cribrosa associated with primary empty sella

D. Perani, G. Scotti, N. Colombo, R. Sterzi, A. Castelli

Research output: Contribution to journalArticlepeer-review


Spontaneous CSF rhinorrhea associated with primary empty sella is a recently recognized condition. Because of its surgical indication, the preoperative evaluation of the possible site of the fistulous tract could be of fundamental importance. Most cases of primary empty sella reported in the literature have shown evidence of leakage through the sellar floor into the sphenoid sinus, thus requiring a transphenoidal approach. Non-traumatic defects in the anterior fossa are rarely reported in the literature. We have collected three new cases in which CT cisternography with non-ionic water-soluble contrast medium ruled out the possibility of a transellar fistula, thus suggesting a possible leak in the area of the lamina cribrosa. This was confirmed by the surgical outcome and by the follow-up of each patient.

Original languageEnglish
Pages (from-to)167-172
Number of pages6
JournalItalian Journal of Neurological Sciences
Issue number2
Publication statusPublished - Jun 1984


  • CSF rhinorrhea
  • Iopamidol CT cisternography
  • primary empty sella

ASJC Scopus subject areas

  • Neuroscience(all)
  • Clinical Neurology


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