Spontaneous DNA damage propels tumorigenicity

I. Vitale, G. Kroemer

Research output: Contribution to journalArticlepeer-review

Abstract

High levels of endogenously generated DNA damage drive oncogenesis, sustain malignant progression and increase therapy resistance. In a paper recently published in Cell Research, Liu and colleagues added additional insights into this topic by uncovering a novel intrinsic source of double-strand breaks that fosters the aggressiveness and stemness of malignant cells.
Original languageEnglish
Pages (from-to)720-721
Number of pages2
JournalCell Research
Volume27
Issue number6
DOIs
Publication statusPublished - Jun 1 2017

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