Abstract
Two cases of spontaneous improvement of optic pathway lesions in neurofibromatosis type 1 are reported. At time of diagnosis the children were aged 21 and 32 months respectively; they have been followed by both MRI and clinical evaluation for 5 and 4 years. MRI findings of the first 19 months of follow-up for Case 1 have been described by us before. On MRI serial evaluation, Case 1 showed an almost complete normalization of the size of lesions and a resolution of enhancement, whereas Case 2 showed a slight decrease in the size of lesions and a resolution of enhancement. From the clinical point of view Case 1 showed a normalization of his clinical signs, whereas in Case 2, a visual improvement was only slight, if at all present. In Case 1, the clinical improvement seemed to follow the spontaneous regression of the lesions detected by MRI.
Original language | English |
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Pages (from-to) | 205-209 |
Number of pages | 5 |
Journal | Neuropediatrics |
Volume | 30 |
Issue number | 4 |
Publication status | Published - Aug 1999 |
Keywords
- MRI
- Neurofibromatosis 1
- Optic glioma
- Optic pathway glioma
ASJC Scopus subject areas
- Clinical Neurology
- Pediatrics, Perinatology, and Child Health