Spontaneous ocular squamous cell carcinoma in twin goats: Pathological and biomolecular studies

M. Marà, G. Di Guardo, A. Venuti, G. Marruchella, C. Palmieri, M. De Rugeriis, L. Petrizzi, P. Simeone, C. Rizzo, L. Della Salda

Research output: Contribution to journalArticle

Abstract

Ocular squamous cell carcinoma (OSCC) is a well-characterized tumour occurring spontaneously in cattle and other mammalian species but not previously reported in the goat. This report describes the histological features of well-differentiated OSCCs in twin goats. Biomolecular investigations led to the identification of Papillomavirus-related DNA sequences within the neoplastic ocular parenchyma of both animals, but immunohistochemical and ultrastructural studies failed to demonstrate viral particles. A putative role of Papillomavirus in the aetiology of OSCC is discussed, together with other possible causative factors.

Original languageEnglish
Pages (from-to)96-100
Number of pages5
JournalJournal of Comparative Pathology
Volume132
Issue number1
DOIs
Publication statusPublished - Jan 2005

Fingerprint

squamous cell carcinoma
Goats
Squamous Cell Carcinoma
Papillomaviridae
eyes
goats
virion
Virion
etiology
nucleotide sequences
neoplasms
cattle
Neoplasms
animals

Keywords

  • Eye
  • Goat
  • Koilocyte
  • Ocular squamous cell carcinoma
  • Papillomavirus
  • Tumour
  • Viral infection

ASJC Scopus subject areas

  • Animal Science and Zoology

Cite this

Marà, M., Di Guardo, G., Venuti, A., Marruchella, G., Palmieri, C., De Rugeriis, M., ... Della Salda, L. (2005). Spontaneous ocular squamous cell carcinoma in twin goats: Pathological and biomolecular studies. Journal of Comparative Pathology, 132(1), 96-100. https://doi.org/10.1016/j.jcpa.2004.06.007

Spontaneous ocular squamous cell carcinoma in twin goats : Pathological and biomolecular studies. / Marà, M.; Di Guardo, G.; Venuti, A.; Marruchella, G.; Palmieri, C.; De Rugeriis, M.; Petrizzi, L.; Simeone, P.; Rizzo, C.; Della Salda, L.

In: Journal of Comparative Pathology, Vol. 132, No. 1, 01.2005, p. 96-100.

Research output: Contribution to journalArticle

Marà, M, Di Guardo, G, Venuti, A, Marruchella, G, Palmieri, C, De Rugeriis, M, Petrizzi, L, Simeone, P, Rizzo, C & Della Salda, L 2005, 'Spontaneous ocular squamous cell carcinoma in twin goats: Pathological and biomolecular studies', Journal of Comparative Pathology, vol. 132, no. 1, pp. 96-100. https://doi.org/10.1016/j.jcpa.2004.06.007
Marà, M. ; Di Guardo, G. ; Venuti, A. ; Marruchella, G. ; Palmieri, C. ; De Rugeriis, M. ; Petrizzi, L. ; Simeone, P. ; Rizzo, C. ; Della Salda, L. / Spontaneous ocular squamous cell carcinoma in twin goats : Pathological and biomolecular studies. In: Journal of Comparative Pathology. 2005 ; Vol. 132, No. 1. pp. 96-100.
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